APSA6720

NEFM Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APSA6720-Each-of-1 In Stock ₹ 50,480.40

APSA6720 - Each of 1

₹ 50,480.40

In Stock

Quantity

1

Base Price: ₹ 50,480.40

GST (18%): ₹ 9,086.472

Total Price: ₹ 59,566.872

Antigen

NEFM

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NEFM

Gene Alias

160 kDa neurofilament protein; major neuronal intermediate filament subunit; medium neurofilament subunit; middle molecular weight neurofilament protein NF-M(2); Nef3; Nefm; nef-m; nefm.S; nefm-a; nefm-b; Neurofilament 3; neurofilament 3 (150kDa medium); neurofilament 3, medium; neurofilament M subunit; neurofilament medium; neurofilament medium polypeptide; neurofilament medium S homeolog; neurofilament medium tail domain; neurofilament protein M; Neurofilament protein, middle polypeptide; neurofilament triplet M protein; neurofilament, medium polypeptide; neurofilament, medium polypeptide 150kDa; neurofilament, medium polypeptide S homeolog; neurofilament-3 (150 kD medium); neurofilament-M; neurofilament-M subunit; neuronal intermediate filament; NF160; NF165; NFM; NF-M; NF-M c-terminus; NF-M protein; NMC; XELAEV_18020229mg

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 5mM sodium azide

Gene Accession No.

O77788, P07197, P08552, P08553, P12839, P16053

Gene Symbols

NEFM

Immunogen

Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M, amino acids 549-845

Regulatory Status

RUO

Gene ID (Entrez)

100054129, 100625407, 18040, 24588, 281347, 396206, 4741

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is likely to react with most mammals
  • Suggested positive control: antigen standard for NEFM (transient overexpression lysate)
  • Neurofilaments (NFs) are a type of intermediate filament (IF) expressed almost exclusively in neuronal cells, and in those cells most prominently in large axons
  • NFs, in most vertebrates, are composed of three different polypeptide chains with different molecular weights - neurofilament medium protein (NF-M), high (NF-H) and light protein (NF-L), which share sequence and structural similarity in a coiled-coil core domain, but differ in the length and sequence of their N-termini and more dramatically of their C-termini which in the case of NF-M and NF-H form the flexible extensions that link NFs to each other and to other elements in the cytoplasm
  • NF-M protein tail-mediated interactions of neurofilaments are critical for size and cytoskeletal architecture of axons, and are mediated, in part, by the highly phosphorylated tail domain of this protein
  • NF-M phosphorylation and O-GlcNAcylation are regulated reciprocally and affect its translocation and filament formation and function
  • Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons and are biochemically very stable.

Compare Similar Items

Show Difference

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Thermo Scientific

APSA6720

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Antigen:
NEFM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEFM

Gene Alias:
160 kDa neurofilament protein; major neuronal intermediate filament subunit; medium neurofilament subunit; middle molecular weight neurofilament protein NF-M(2); Nef3; Nefm; nef-m; nefm.S; nefm-a; nefm-b; Neurofilament 3; neurofilament 3 (150kDa medium); neurofilament 3, medium; neurofilament M subunit; neurofilament medium; neurofilament medium polypeptide; neurofilament medium S homeolog; neurofilament medium tail domain; neurofilament protein M; Neurofilament protein, middle polypeptide; neurofilament triplet M protein; neurofilament, medium polypeptide; neurofilament, medium polypeptide 150kDa; neurofilament, medium polypeptide S homeolog; neurofilament-3 (150 kD medium); neurofilament-M; neurofilament-M subunit; neuronal intermediate filament; NF160; NF165; NFM; NF-M; NF-M c-terminus; NF-M protein; NMC; XELAEV_18020229mg

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 5mM sodium azide

Gene Accession No.:
O77788, P07197, P08552, P08553, P12839, P16053

Gene Symbols:
NEFM

Immunogen:
Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M, amino acids 549-845

Regulatory Status:
RUO

Gene ID (Entrez):
100054129, 100625407, 18040, 24588, 281347, 396206, 4741

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

APSA6723

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Antigen:
Peripherin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRPH

Gene Alias:
if3; nef4; Neurofilament 4; neurofilament 4 (57kD); neuronal intermediate filament IF3; Perf; Peripherin; peripherin 1; peripherin L homeolog; plasticin; PRPH; prph.L; PRPH1; XELAEV_18013332mg; XIF3

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mammalia, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 5mM sodium azide

Gene Accession No.:
A6QQJ3, P15331, P21807, P41219

Gene Symbols:
PRPH

Immunogen:
Full-length recombinant human peripherin expressed in and purified form E.coli.

Regulatory Status:
RUO

Gene ID (Entrez):
100152434, 19132, 24688, 510082, 5630

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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APSA6725

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Antigen:
alpha Internexin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INA

Gene Alias:
66 kDa neurofilament protein; Alpha-internexin; alpha-Inx; AV028420; FLJ18662; FLJ57501; Ina; Inexa; internexin neuronal intermediate filament protein alpha; internexin neuronal intermediate filament protein, alpha; internexin, alpha; Intlaa; LOW QUALITY PROTEIN: alpha-internexin; MGC12702; NEF5; Neuro; Neurofilament 5; neurofilament 5 (66kD); Neurofilament 66; neurofilament-66; neurofilament-66, tax-binding protein; Nf66; NF-66; TXBP-1

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Equine, Human, Mammalia, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
P23565, P46660, Q08DH7, Q16352

Gene Symbols:
INA

Immunogen:
Purified recombinant rat a-internexin

Regulatory Status:
RUO

Gene ID (Entrez):
100059769, 100153400, 226180, 24503, 532236, 9118

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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APSA6762

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Antigen:
PEN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSENEN

Gene Alias:
1700023M09Rik; gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; liver regeneration-related protein LRRGT00140; LRRGT00140 mRNA; MDS033; MSTP064; Pen2; Pen-2; presenilin enhancer 2; presenilin enhancer 2 homolog; presenilin enhancer 2 homolog (C. elegans); presenilin enhancer gamma secretase subunit; presenilin enhancer gamma-secretase subunit; presenilin enhancer protein 2; presenilin enhancer, gamma-secretase subunit; Psenen; RGD1312037

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q9CQR7, Q9NZ42

Gene Symbols:
PSENEN

Immunogen:
A synthetic peptide corresponding to the C-terminus of human PEN2 (within residues 50-101). [UniProt# Q9NZ42]

Regulatory Status:
RUO

Gene ID (Entrez):
55851, 66340

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid