BDB340507

PAC-1 Mouse anti-Human, FITC, Clone: PAC-1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB340507-Each-of-1 In Stock ₹ 26,010.24

BDB340507 - Each of 1

₹ 26,010.24

In Stock

Quantity

1

Base Price: ₹ 26,010.24

GST (18%): ₹ 4,681.843

Total Price: ₹ 30,692.083

Antigen

PAC-1

Classification

Monoclonal

Concentration

25μg/mL

Formulation

Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen

Human platelets

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Applications

Flow Cytometry

Clone

PAC-1

Conjugate

FITC

Host Species

Mouse

Quantity

50 Tests

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgM κ

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Description

  • PAC-1 recognizes an epitope on the glycoprotein IIb/IIIa (gpIIb/IIIa, aIIbb3) complex of activated platelets at or near the platelet fibrinogen receptor
  • The gpIIb/IIIa complex is a member of a family of heterodimeric adhesive protein receptors found on a variety of cell types that have been named the integrin or the cytoadhesion family.The gpIIb/IIIa complex is located on the surface membrane of resting platelets
  • Platelet activation induces a calcium-dependent conformational change in gpIIb/IIIa that exposes a ligand binding site
  • Four adhesive macromolecules are capable of interacting with the activated form of gpIIb/IIIa: fibrinogen, von Willebrand factor (vWf), fibronectin, and vitronectin
  • The binding of fibrinogen to the gpIIb/IIIa receptor is required for platelet aggregation
  • PAC-1 binds only to activated platelets and appears to be specific for this recognition site within gpIIb/IIIa
  • Approximately 45,000 to 50,000 gpIIb/IIIa receptors appear on the platelet surface upon activation
  • PAC-1 inhibits fibrinogen- mediated platelet aggregation
  • Flow Cytometry

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB340507

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Antigen:
PAC-1

Classification:
Monoclonal

Concentration:
25μg/mL

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Human platelets

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Applications:
Flow Cytometry

Clone:
PAC-1

Conjugate:
FITC

Host Species:
Mouse

Quantity:
50 Tests

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgM κ

Img

BD Biosciences

BDB340508

--


Antigen:
IL-13

Classification:
Monoclonal

Concentration:
__

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Human Recombinant IL-13

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
JES10-5A2

Conjugate:
PE

Host Species:
Rat

Quantity:
50 Tests

Research Discipline:
__

Target Species:
Human

Isotype:
IgG1

Img

BD Biosciences

BDB340509

--


Antigen:
IL-8

Classification:
Monoclonal

Concentration:
__

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Recombinant human IL-8

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
AS14

Conjugate:
FITC

Host Species:
Mouse

Quantity:
50 Tests

Research Discipline:
__

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB340512

--


Antigen:
TNF alpha

Classification:
Monoclonal

Concentration:
__

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Recombinant human TNF-a

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
6401.1111

Conjugate:
PE

Host Species:
Mouse

Quantity:
50 Tests

Research Discipline:
__

Target Species:
Human

Isotype:
IgG1 κ