BDB340535

PAC-1 Mouse anti-Human, Unlabeled, Clone: PAC-1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB340535-Each-of-1 In Stock ₹ 39,870.96

BDB340535 - Each of 1

₹ 39,870.96

In Stock

Quantity

1

Base Price: ₹ 39,870.96

GST (18%): ₹ 7,176.773

Total Price: ₹ 47,047.733

Antigen

PAC-1

Classification

Monoclonal

Concentration

1mg/mL

Formulation

Phosphate buffered saline with 0.01% sodium azide.

Immunogen

Human platelets

Quantity

200 μg

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgM κ

Applications

Flow Cytometry

Clone

PAC-1

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Related Products

Img

BD Biosciences

BDB340507

--

Img

BD Biosciences

BDB340976

--

Img

BD Biosciences

BDB346310

--

Img

BD Biosciences

BDB347830

--

Img

BD Biosciences

BDB347740

--

Img

BD Biosciences

BDB348040

--

Img

BD Biosciences

BDB347340

--

Img

BD Biosciences

BDB347530

--

Description

  • PAC-1 recognizes an epitope on the glycoprotein IIb/IIIa (gpIIb/IIIa, aIIbb3) complex of activated platelets at or near the platelet fibrinogen receptor
  • The gpIIb/IIIa complex is a member of a family of heterodimeric adhesive protein receptors found on a variety of cell types that have been named the integrin or the cytoadhesion family.The gpIIb/IIIa complex is located on the surface membrane of resting platelets
  • Platelet activation induces a calcium-dependent conformational change in gpIIb/IIIa that exposes a ligand binding site
  • Four adhesive macromolecules are capable of interacting with the activated form of gpIIb/IIIa: fibrinogen, von Willebrand factor (vWf), fibronectin, and vitronectin
  • The binding of fibrinogen to the gpIIb/IIIa receptor is required for platelet aggregation
  • PAC-1 binds only to activated platelets and appears to be specific for this recognition site within gpIIb/IIIa
  • Approximately 45,000 to 50,000 gpIIb/IIIa receptors appear on the platelet surface upon activation
  • PAC-1 inhibits fibrinogen- mediated platelet aggregation
  • Flow Cytometry, Immunohistochemistry

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB340535

--


Antigen:
PAC-1

Classification:
Monoclonal

Concentration:
1mg/mL

Formulation:
Phosphate buffered saline with 0.01% sodium azide.

Immunogen:
Human platelets

Quantity:
200 μg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
PAC-1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Img

Fischer Scientific

BDB340536

--


Antigen:
CD161

Classification:
Monoclonal

Concentration:
__

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Human NKR-P1A Transfected Mouse Fibroblasts

Quantity:
50 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
DX12

Conjugate:
FITC

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Img

BD Biosciences

BDB340544

--


Antigen:
CD11c

Classification:
Monoclonal

Concentration:
__

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Human Hairy-Cell Leukemia Cells

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
S-HCL-3

Conjugate:
APC

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Img

BD Biosciences

BDB340545

--


Antigen:
CD123

Classification:
Monoclonal

Concentration:
12.5μg/mL

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Human IL-3Rα Transfected Cell Line

Quantity:
50 Tests

Research Discipline:
__

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
9F5

Conjugate:
PE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.