BDB347314
CD8 Mouse anti-Human, PerCP, Clone: SK1, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB347314-Each-of-1 | In Stock | ₹ 64,426.68 |
BDB347314 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 64,426.68
GST (18%): ₹ 11,596.802
Total Price: ₹ 76,023.482
Antigen
CD8
Classification
Monoclonal
Concentration
6.25μg/mL
Formulation
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen
Human Peripheral Blood T Cells
Quantity
100 Tests
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
SK1
Conjugate
PerCP
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Related Products
Description
- CD8 recognizes the 32-kilodalton (kd) α-subunit of a disulfide-linked bimolecular complex.The majority of peripheral blood CD8+ T lymphocytes expresses an α/β heterodimer (Mr 32, 30 kd), while CD8+ CD16+ natural killer (NK) lymphocytes and CD8+ T-cell receptor (TCR)-γ/δ + T lymphocytes express an α/α homodimer (Mr 30 kd)
- CD8+ TCR-α/β+ T lymphocytes can express either an α/α homodimer or α/β heterodimer
- The CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules, resulting in increased adhesion between the CD8+ T lymphocytes and target cells.Binding of the CD8 antigen to class I MHC molecules enhances the activation of resting T lymphocytes.The CD8 antigen is coupled to a protein tyrosine kinase, p56 lck
- The CD8:p56 lck complex can play a role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex
- The CD8 antigen is present on the human suppressor/cytotoxic T-lymphocyte subset as well as on a subset of NK lymphocytes.The CD8 antigen is expressed on 19% to 48% of normal peripheral blood lymphocytes and 60% to 85% of normal thymocytes.The CD8+ T- and NK-lymphocyte subsets can be further subdivided into the following groups: CD16+ NK lymphocytes that can express the CD8 antigen in low density;CD57+ T lymphocytes that express high-density CD8 antigen;and CD8+CD62L+ lymphocytes that collaborate with CD8+ CD62Ln++hocytes to generate suppression of B-lymphocyte function.CD8 cross-reacts with lymphocytes of some nonhuman primate species Flow Cytometry
Compare Similar Items
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Antigen: CD8
Classification: Monoclonal
Concentration: 6.25μg/mL
Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen: Human Peripheral Blood T Cells
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: SK1
Conjugate: PerCP
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Antigen:
CD8
Classification:
Monoclonal
Concentration:
6.25μg/mL
Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen:
Human Peripheral Blood T Cells
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
SK1
Conjugate:
PerCP
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Antigen: CD4
Classification: Monoclonal
Concentration: 3.0μg/mL
Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen: Human Peripheral Blood T Cells
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: SK3
Conjugate: Biotin
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Antigen:
CD4
Classification:
Monoclonal
Concentration:
3.0μg/mL
Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen:
Human Peripheral Blood T Cells
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
SK3
Conjugate:
Biotin
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Antigen: CD4
Classification: Monoclonal
Concentration: 3.2μg/mL
Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen: Human Peripheral Blood T Cells
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: SK3
Conjugate: PerCP
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Antigen:
CD4
Classification:
Monoclonal
Concentration:
3.2μg/mL
Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen:
Human Peripheral Blood T Cells
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
SK3
Conjugate:
PerCP
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Antigen: CD4
Classification: Monoclonal
Concentration: 3.1μg/mL
Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen: Human Peripheral Blood T Cells
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: SK3
Conjugate: PE
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Antigen:
CD4
Classification:
Monoclonal
Concentration:
3.1μg/mL
Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen:
Human Peripheral Blood T Cells
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
SK3
Conjugate:
PE
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.