BDB551051
Bcl-2 w/control Hamster anti-Human, Unlabeled, Clone: 6C8, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB551051-Each-of-1 | In Stock | ₹ 24,598.50 |
BDB551051 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,598.50
GST (18%): ₹ 4,427.73
Total Price: ₹ 29,026.23
Antigen
Bcl-2 w/control
Classification
Monoclonal
Conjugate
Unconjugated
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG
Applications
Western Blot
Clone
6C8
Host Species
Hamster
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Related Products
Description
- Bcl-2 is considered to be novel among proto-oncogenes because it blocks apoptosis (programmed cell death) in many cell types
- Apoptosis is an active form of cellular suicide that typically requires new RNA and protein synthesis and is associated with distinct morphological changes including cell shrinkage, cytoplasm membrane blebbing, nuclear fragmentation and DNA degradation
- The Bcl-2 gene was first found in t(14:18) containing follicular B-cell lymphomas
- A high proportion of these lymphomas contains t(14:18) chromosomal translocations involving the human Bcl-2 gene
- Translocation of Bcl-2 sequences from chromosome 18 onto the transcriptionally active immunoglobulin locus at chromosome band 14q32 in B-cells deregulates Bcl-2 gene expression, resulting in high levels of Bcl-2 mRNA and protein expression
- Because Bcl-2 blocks apoptosis, it may contribute to tumorigenesis by prolonged cell survival rather than by accelerating the rate of cell proliferation
- The reduced molecular weight of Bcl-2 is 26 kDa
- Additional minor bands at 27-31 kDa and 18-21 kDa may also be observed.
Compare Similar Items
Show Difference
Antigen: Bcl-2 w/control
Classification: Monoclonal
Conjugate: Unconjugated
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG
Applications: Western Blot
Clone: 6C8
Host Species: Hamster
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Bcl-2 w/control
Classification:
Monoclonal
Conjugate:
Unconjugated
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG
Applications:
Western Blot
Clone:
6C8
Host Species:
Hamster
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: CD85j
Classification: Monoclonal
Conjugate: PE
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: GHI/75
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD85j
Classification:
Monoclonal
Conjugate:
PE
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
GHI/75
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD112
Classification: Monoclonal
Conjugate: PE
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: R2.525
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD112
Classification:
Monoclonal
Conjugate:
PE
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
R2.525
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD83
Classification: Monoclonal
Conjugate: PE-Cyanine5
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: HB15E
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD83
Classification:
Monoclonal
Conjugate:
PE-Cyanine5
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
HB15E
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.