BDB554293
p53 Mouse anti-Human, Unlabeled, Clone: DO-1, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB554293-Each-of-1 | In Stock | ₹ 29,261.52 |
BDB554293 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,261.52
GST (18%): ₹ 5,267.074
Total Price: ₹ 34,528.594
Antigen
p53
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human p53
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Bovine, Human
Isotype
IgG2a
Applications
Western Blot
Clone
DO-1
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- The gene for the nuclear phosphoprotein p53 is the most commonly mutated gene yet identified in human cancers
- Missense mutations occur in tumors of the colon, lung, breast, ovary, bladder and several other organs
- The mutant p53 is overexpressed in a variety of transformed cells and wild-type p53 forms specific complexes with several viral oncogenes including SV40 large T, E1B from adenovirus, and E6 from human papilloma virus
- Wild type p53 plays a role as a checkpoint protein for DNA damage during the G1/S-phase of the cell cycle
- However, it is still unclear, whether point mutated forms of p53 are simple null mutants and/or dominant negatively acting proteins
- DO-1 reacts with human wild-type and mutant p53
- It cross-reacts with bovine p53 but does not cross-react with mouse or rat p53
- DO-1 recognizes an epitope between amino acids 1 and 45 of all known forms of human p53
- Human recombinant p53 protein was used as immunogen
- Host Species: Mouse Clone: DO-1 Isotype: IgG2a Species Reactivity: Human Immunogen: Human p53 Formula Weight [Chemical]: 53kDa Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blotting
Compare Similar Items
Show Difference
Antigen: p53
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human p53
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Bovine, Human
Isotype: IgG2a
Applications: Western Blot
Clone: DO-1
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
p53
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human p53
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Bovine, Human
Isotype:
IgG2a
Applications:
Western Blot
Clone:
DO-1
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: p53
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human Recombinant p53 protein
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Bovine, Human, Monkey
Isotype: IgG2b
Applications: Flow Cytometry, Western Blot
Clone: DO-7
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
p53
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human Recombinant p53 protein
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Bovine, Human, Monkey
Isotype:
IgG2b
Applications:
Flow Cytometry, Western Blot
Clone:
DO-7
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: p53
Classification: Monoclonal
Concentration: __
Formulation: __
Immunogen: __
Quantity: 100 Tests
Research Discipline: Cell Biology
Target Species: Bovine, Human, Monkey
Isotype: IgG2b
Applications: Flow Cytometry
Clone: DO-7
Conjugate: FITC
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
p53
Classification:
Monoclonal
Concentration:
__
Formulation:
__
Immunogen:
__
Quantity:
100 Tests
Research Discipline:
Cell Biology
Target Species:
Bovine, Human, Monkey
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
DO-7
Conjugate:
FITC
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: IL-2
Classification: Monoclonal
Concentration: 1.0mg/mL
Formulation: No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen: T cell clone supernatant
Quantity: 0.5 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a
Applications: Neutralization
Clone: S4B6
Conjugate: Unconjugated
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
IL-2
Classification:
Monoclonal
Concentration:
1.0mg/mL
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen:
T cell clone supernatant
Quantity:
0.5 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a
Applications:
Neutralization
Clone:
S4B6
Conjugate:
Unconjugated
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C