BDB554285

JNK1/JNK2 Mouse anti-Human, Unlabeled, Clone: G151-666, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554285-Each-of-1 In Stock ₹ 32,683.92

BDB554285 - Each of 1

₹ 32,683.92

In Stock

Quantity

1

Base Price: ₹ 32,683.92

GST (18%): ₹ 5,883.106

Total Price: ₹ 38,567.026

Antigen

JNK1/JNK2

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human JNK1 Fusion Protein

Quantity

0.1 mg

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgG2a

Applications

Western Blot

Clone

G151-666

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • C-Jun NH2-terminal kinase (JNK) binds to the c-Jun terminal transactivation domain and phosphorylates it on Ser-63 and Ser-73
  • Phosphorylation enhances the transcriptional activity of c-Jun
  • The Ser-Pro-acidic sequence targeted by JNK kinase activity establishes it as a prolinedirected kinase related to the MAP kinases and cyclin/dependent kinases
  • JNK may act as a tumor promoter in response to UV-irradiation since its activity is potently stimulated by radiation
  • This has relevance to observations that c-Jun transcriptional activity is upregulated by UV irradiation
  • In addition to UV irradiation, JNK is also activated by some other forms of cellular stress, including heatshock
  • Both the JNK1 (46kDa) and JNK2 (54kDa) isozymes appear equally capable of binding to the c-Jun terminal transactivation domain following induction by UV irradiation or heatshock
  • G151-666 recognizes both the JNK1 and JNK2 isozymes of JNK1
  • A bacterially expressed fusion protein of human JNK1 was used as immunogen
  • Host Species: Mouse Clone: G151-666 Isotype: IgG2a Species Reactivity: Human Immunogen: Human JNK1 Fusion Protein Immunoprecipitation, Western Blotting

Compare Similar Items

Show Difference

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BD Biosciences

BDB554285

--


Antigen:
JNK1/JNK2

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human JNK1 Fusion Protein

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG2a

Applications:
Western Blot

Clone:
G151-666

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB554292

--


Antigen:
Maspin

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant Human Maspin

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG2b

Applications:
Western Blot

Clone:
G167-70

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB554293

--


Antigen:
p53

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human p53

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Bovine, Human

Isotype:
IgG2a

Applications:
Western Blot

Clone:
DO-1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB554294

--


Antigen:
p53

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human Recombinant p53 protein

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Bovine, Human, Monkey

Isotype:
IgG2b

Applications:
Flow Cytometry, Western Blot

Clone:
DO-7

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C