BDB554266

FLI-1 Mouse anti-Human, Unlabeled, Clone: G146-222, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554266-Each-of-1 In Stock ₹ 32,855.04

BDB554266 - Each of 1

₹ 32,855.04

In Stock

Quantity

1

Base Price: ₹ 32,855.04

GST (18%): ₹ 5,913.907

Total Price: ₹ 38,768.947

Antigen

FLI-1

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Fli-1 ets Domain Fusion Protein

Quantity

0.1 mg

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgG2b

Applications

Western Blot

Clone

G146-222

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • Fli-1 is a 50kDa ets-related transcription factor
  • Like other ets-related proteins it binds to consensus sites in DNA through an 85 amino acid ets domain in the carboxyl region of the protein
  • Fli-1 is associated with Ewing sarcoma (EWS) through a t(11;22)(q24;q12) chromosomal translocation
  • This translocation brings the 5' region of the EWS gene into conjunction with the 3' region of the Fli-1 gene encoding the ets-DNA binding domain
  • Such a translocation is found in 85% of Ewing sarcomas
  • The resulting fusion protein has the DNA binding activity of Fli- 1 and, with the EWS domain, it is also a more potent transcriptional activator than Fli-1 itself
  • The strong transforming activity of the EWS-Fli-1 fusion protein may in part be due to its ability to transactivate the promoter for c-myc
  • G146-222 recognizes human Fli-1
  • The antibody was raised against a bacterially expressed Fli-1 ets domain fusion protein
  • Host Species: Mouse Clone: G146-222 Isotype: IgG2b Species Reactivity: Human Immunogen: Fli-1 ets Domain Fusion Protein Formula Weight [Chemical]: 50kDa Immunoprecipitation, Western Blotting

Compare Similar Items

Show Difference

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BD Biosciences

BDB554266

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Antigen:
FLI-1

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Fli-1 ets Domain Fusion Protein

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG2b

Applications:
Western Blot

Clone:
G146-222

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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BDB554268

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Antigen:
PU.1

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
PU.1 Fusion Protein

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG2a

Applications:
Western Blot

Clone:
G148-74

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
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Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
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Immunogen:
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Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG2a

Applications:
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Clone:
14.G2A

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
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Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
5G3

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C