BDB551244
Caspase-8 Mouse anti-Human, Unlabeled, Clone: 4-1-20, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB551244-Each-of-1 | In Stock | ₹ 24,470.16 |
BDB551244 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,470.16
GST (18%): ₹ 4,404.629
Total Price: ₹ 28,874.789
Antigen
Caspase-8
Classification
Monoclonal
Concentration
0.5mg/mL
Description
FLICE, MACH-1, Mch5
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Western Blot
Clone
4/1/2020
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human caspase-8 recombinant protein
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Caspase-8 (FLICE/MACH-1) is a 55 kDa cytosolic protein with homology to the CD95/Fas-associated signal transducer, FADD/MORT-1, as well as to other caspase (ICE/Ced-3) cysteine proteases
- The N-terminal region of caspase-8 contains an amino acid sequence, termed the death domain, that facilitates caspase-8-FADD direct interaction
- FADD therefore acts as an adapter molecule, allowing caspase-8 to become recruited to the cytoplasmic region of Fas following receptor activation
- Viral proteins (v-FLIPS) which inhibit recruitment and activation of caspase-8 have been isolated
- Caspase-8 is produced as a proenzyme (55/50 kDa doublet) which upon receptor aggregation is proteolytically cleaved into smaller subunits of 40/36 (doublet), and 23 kDa
- Overexpression of caspase-8 is sufficient to induce apoptosis in certain cell lines (e.g., MCF-7) and this phenotype is blocked by overexpression of the caspase-3 protease inhibitor, CrmA
- The antibody recognizes both the proform of human caspase-8 (55/50 kDa doublet) as well as the cleaved form (40/36 kDa doublet) on SDS/PAGE
- Full-length recombinant human caspase-8 protein was used as immunogen.
Compare Similar Items
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Antigen: Caspase-8
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: FLICE, MACH-1, Mch5
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: 4/1/2020
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human caspase-8 recombinant protein
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
Caspase-8
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
FLICE, MACH-1, Mch5
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
4/1/2020
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human caspase-8 recombinant protein
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Caspase-9
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: ICE-LAP-6, Mch6, Apaf-3
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: 2-22
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human caspase-9 N-terminal fragment aa 1-134
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
Caspase-9
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
ICE-LAP-6, Mch6, Apaf-3
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
2-22
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human caspase-9 N-terminal fragment aa 1-134
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD209
Classification: Monoclonal
Concentration: 31.25μg/mL
Description: DC-SIGN
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: DCN46
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
Immunogen: Human Monocyte Derived DC Cells
Quantity: 1 mL
Research Discipline: Immunology
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD209
Classification:
Monoclonal
Concentration:
31.25μg/mL
Description:
DC-SIGN
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
DCN46
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
Immunogen:
Human Monocyte Derived DC Cells
Quantity:
1 mL
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD31
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: PECAM-1
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: MEC 13.3
Conjugate: APC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: 129/Sv mouse-derived endothelioma cell line tEnd.1
Quantity: 100 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD31
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
PECAM-1
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
MEC 13.3
Conjugate:
APC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
129/Sv mouse-derived endothelioma cell line tEnd.1
Quantity:
100 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ