BDB554073

MLH1 Mouse anti-Human, Unlabeled, Clone: G168-728, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554073-Each-of-1 In Stock ₹ 31,956.66

BDB554073 - Each of 1

₹ 31,956.66

In Stock

Quantity

1

Base Price: ₹ 31,956.66

GST (18%): ₹ 5,752.199

Total Price: ₹ 37,708.859

Antigen

MLH1

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Recombinant Human MLH

Quantity

0.1 mg

Research Discipline

Cell Biology

Target Species

Human, Mouse

Isotype

IgG2a κ

Applications

Western Blot

Clone

G168-728

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • The repair of mismatched DNA is essential to maintaining the integrity of genetic information over time
  • Loss of function of DNA repair enzymes can lead to an accumulation of replication errors, resulting in a mutated phenotype
  • DNA repair enzymes are highly conserved from bacteria to yeast to mammals
  • In yeast the proteins are called MutS homolog 2 (MSH2), MutL homolog (MLH1), and PMS1 which is also a homolog of MutL
  • MSH2 is involved in the initial recognition of mismatched nucleotides during the replication mismatch repair process
  • It is thought that after MSH2 binds to a mismatched DNA duplex, it is joined by a heterodimer of MLH1 and PMS1 which together help facilitate the later steps in mismatch repair
  • The G168-728 antibody recognizes human and mouse MLH1 (80-85kDa)
  • Full-length human recombinant MLH was expressed as a maltose binding-MLH fusion protein, affinity purified, and used as immunogen
  • Host Species: Mouse Clone: G168-728 Isotype: IgG2a κ Species Reactivity: Human Immunogen: Recombinant Human MLH Formula Weight [Chemical]: 80-85kDa Immunoprecipitation, Western Blotting

Compare Similar Items

Show Difference

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BD Biosciences

BDB554073

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Antigen:
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Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant Human MLH

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
G168-728

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
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Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
12.14

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

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Store undiluted at 4°C

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Formulation:
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Quantity:
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Research Discipline:
Cell Biology

Target Species:
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Isotype:
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Applications:
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Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

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Content And Storage:
Store undiluted at 4°C

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Classification:
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Concentration:
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Formulation:
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Immunogen:
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Quantity:
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Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
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Applications:
Flow Cytometry

Clone:
GNS-1

Conjugate:
FITC

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.