BDB551303

CD8a Mouse anti-Pig, FITC, Clone: 76-2-11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB551303-Each-of-1 In Stock ₹ 24,641.28

BDB551303 - Each of 1

₹ 24,641.28

In Stock

Quantity

1

Base Price: ₹ 24,641.28

GST (18%): ₹ 4,435.43

Total Price: ₹ 29,076.71

Antigen

CD8a

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

dd miniature swine thymocytes

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Porcine

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

76-2-11

Conjugate

FITC

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 76-2-11 (also known as clone PT8) antibody reacts with an epitope on the CD8α chain, a 35kDa antigen expressed on thymocytes, peripheral T lymphocytes, and NK cells
  • The CD8 molecule can exist as a 70kDa homodimer, composed of α chains, or heterodimer, composed of an α and β chain
  • Cells which express the CD8αα homodimer display dimmer staining with mAb 76-2-11 than CDαβ-expressing cells
  • The 76-2-11 mAb does not cross-react with human or bovine cells
  • Two peripheral CD8+ T-cell populations can be distinguished in the pig: CD8-bright CD4- CTL effectors/precursors and CD8-dull CD4+ T-helper lymphocytes
  • Pig NK cells express CD8 (dull staining), CD2, MHC class II, LFA-1, and asialo-GM1, but not CD3, CD4, CD5, or CD6
  • mAb 76-2-11 has been reported to partially inhibit in vitro cytotoxic activity of PBL to allogeneic leukocytes, but not NK-cell-mediated lysis, and to deplete CD8+ T cells in vivo
  • This clone was clustered as anti-CD8a at the First International Swine CD workshop
  • Host Species: Mouse Clone: 76-2-11 Isotype: IgG2a κ Species Reactivity: Porcine Immunogen: dd miniature swine thymocytes Flow Cytometry

Compare Similar Items

Show Difference

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BD Biosciences

BDB551303

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Antigen:
CD8a

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
dd miniature swine thymocytes

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Porcine

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
76-2-11

Conjugate:
FITC

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
ELISA

Clone:
AN-18

Conjugate:
Unconjugated

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
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Classification:
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Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Quantity:
0.5 mg

Research Discipline:
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Target Species:
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Isotype:
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Applications:
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Clone:
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Conjugate:
Unconjugated

Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
TROP-2

Classification:
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Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Quantity:
100 μg

Research Discipline:
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Target Species:
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Isotype:
IgG1 κ

Applications:
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Clone:
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Conjugate:
Unconjugated

Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C