BDB553656

CD154 Hamster anti-Mouse, Unlabeled, Clone: MR1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB553656-Each-of-1 In Stock ₹ 28,748.16

BDB553656 - Each of 1

₹ 28,748.16

In Stock

Quantity

1

Base Price: ₹ 28,748.16

GST (18%): ₹ 5,174.669

Total Price: ₹ 33,922.829

Antigen

CD154

Classification

Monoclonal

Concentration

0.5mg/mL

Description

CD40 Ligand, gp39

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

MR1

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Activated mouse Th1 clone D1.6

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG κ3

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Description

  • The MR1 antibody reacts with CD154 (CD40 Ligand, gp39), an accessory molecule expressed on activated T helper (CD4+) lymphocytes
  • CD154 has also been detected on other types of leukocytes, including CD8+ T cells, medullary thymocytes, activated CD4+ NK-T cells, and human NK cells
  • CD154 plays an important role in costimulatory interactions between T and B lymphocytes and between antigen-presenting cells and lymphocytes, regulating the immune response at multiple levels
  • MR1 mAb inhibits in vitro activation of B lymphocytes by T helper cells by blocking interaction of gp39 with CD40
  • In vitro interactions of T cells and antigen-presenting cells can also be blocked by the MR1 antibody
  • In vivo treatment with MR1 antibody blocks the development of experimental autoimmune disease, inhibits formation of germinal centers and generation of memory B cells, reduces T-lymphocyte responses to allogeneic cells and allografts, prevents intrathymic deletion of self-reactive T lymphocytes, and disrupts antigen-specific T-cell responses.

Compare Similar Items

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Img

BD Biosciences

BDB553656

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Antigen:
CD154

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
CD40 Ligand, gp39

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
MR1

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Activated mouse Th1 clone D1.6

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG κ3

Img

Fischer Scientific

BDB553658

--


Antigen:
CD154

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CD40 Ligand, gp39

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MR1

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Activated mouse Th1 clone D1.6

Quantity:
0.2 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG κ3

Img

BD Biosciences

BDB553663

--


Antigen:
Vβ 8.3 T-Cell Receptor

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
__

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1B3.3

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Vβ 8.3 TCR-expressing mouse Th1 clone 3.L2

Quantity:
0.25 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG3

Img

Fischer Scientific

BDB553666

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Antigen:
T- and B-Cell Activation Antigen

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
GL7

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
GL7

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
In vitro-activated T-cell-depleted CBA/Ca mouse splenocytes

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgM κ