BDB553859

Vβ 8 T-Cell Receptor Mouse anti-Mouse, Unlabeled, Clone: F23.1, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB553859-Each-of-1 In Stock ₹ 23,101.20

BDB553859 - Each of 1

₹ 23,101.20

In Stock

Quantity

1

Base Price: ₹ 23,101.20

GST (18%): ₹ 4,158.216

Total Price: ₹ 27,259.416

Antigen

Vβ 8 T-Cell Receptor

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

BALB.B Mouse Lymph-Node and Spleen T Cells

Quantity

0.25 mg

Research Discipline

Immunology

Target Species

Bovine, Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

F23.1

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • Description The F23.1 antibody reacts with the Vβ 8.1, Vβ 8.2, and Vβ 8.3 T-cell receptors (TCR) of mice having the b haplotype (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C58, DBA/1, DBA/2) of the Tcrb gene complex
  • The Tcrb-V8 subfamily gene loci are deleted in mice having the a (e.g., C57BR, C57L, SJL, SWR) or c (e.g., RIII) haplotype
  • Vβ 8.1 TCR-bearing T lymphocytes are clonally eliminated in mice expressing superantigen coded by Mtv-7 (Mls-1a, Mlsa) provirus (e.g., AKR, CBA/J, C58, DBA/2), and activation or elimination of Vβ 8.1 TCR-expressing T cells by this determinant is partially dependent upon presentation by I-E
  • Mtv-43 and/or exogenous MMTV-SW superantigens also cause incomplete elimination of Vβ 8.1 TCR-bearing T cells
  • In addition to expression on conventional T lymphocytes, Vβ 8.2 is the predominant β chain of the TCR on NK-T cells
  • Staphylococcal enterotoxin B, in association with antigen-presenting cells expressing I-A and/or I-E, stimulates lymphocytes bearing Vβ 8 TCR and selectively eliminates those T cells in vivo
  • Soluble and plate-bound F23.1 antibody activates Vβ 8 TCR-bearing T cells, soluble antibody blocks cytolysis mediated by Vβ 8 TCR-bearing cytotoxic T lymphocytes, and in vivo treatment of neonatal mice can arrest intrathymic maturation of Vβ 8 TCR-bearing T cells
  • Host Species: Mouse Clone: F23.1 Isotype: IgG2a κ Species Reactivity: Mouse Immunogen: BALB.B Mouse Lymph-Node and Spleen T Cells ELISA, Flow Cytometry, Immunoprecipitation, Western Blotting

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Antigen:
Vβ 8 T-Cell Receptor

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
BALB.B Mouse Lymph-Node and Spleen T Cells

Quantity:
0.25 mg

Research Discipline:
Immunology

Target Species:
Bovine, Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
F23.1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Vβ 8 T-Cell Receptor

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Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
BALB.B Mouse Lymph-Node and Spleen T Cells

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
F23.1

Conjugate:
PE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Research Discipline:
Cell Biology

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Mouse

Isotype:
IgM κ

Applications:
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Clone:
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Conjugate:
Unconjugated

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
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Store undiluted at 4°C

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Immunogen:
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Quantity:
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Research Discipline:
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Target Species:
Mouse

Isotype:
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Applications:
Flow Cytometry

Clone:
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Conjugate:
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Purification Method:
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Primary or Secondary:
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Content And Storage:
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