BDB554450

CD121b Rat anti-Mouse, PE, Clone: 4E2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554450-Each-of-1 In Stock ₹ 34,224.00

BDB554450 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

CD121b

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Il1r2; IL-1RII; IL-1R2; Il1rb; IL-1Rβ; IL-1R-beta; IL-1 receptor beta chain

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

4.00E+02

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse IL-1RII Protein

Quantity

0.2 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2a κ

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Description

  • The 4E2 monoclonal antibody specifically binds to CD121b which is also known as the IL-1 receptor type II (IL-1RII, IL-1R2) or IL-1 receptor beta (IL-1R-beta, IL-1Rβ)
  • CD121b is encoded by the Il1r2 gene and presents as a 68 kDa type I transmembrane glycoprotein
  • It is expressed on a variety of cell types including B cells, neutrophils, monocytes, and bone marrow progenitor cells
  • A soluble form of CD121b is produced by proteolysis especially after cellular activation
  • Unlike the IL-1 type I receptor (CD121a), CD121b has a short cytoplasmic domain and does not mediate IL-1 signaling
  • CD121b may function in a membrane or soluble form as a decoy receptor that can bind IL-1 and reduce its effective concentration and biological activity
  • The 4E2 antibody blocks IL-1 binding to the IL-1 receptor type II.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB554450

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Antigen:
CD121b

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Il1r2; IL-1RII; IL-1R2; Il1rb; IL-1Rβ; IL-1R-beta; IL-1 receptor beta chain

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
4.00E+02

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse IL-1RII Protein

Quantity:
0.2 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB554457

--


Antigen:
CD132

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Il2rg; IL-2Rγ; Commin gamma chain; Common γ; gamma c receptor; γc

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
4G3

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
__

Quantity:
0.2 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB554462

--


Antigen:
CD126

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Il6ra; IL-6 Receptor α chain; IL-6RA; IL-6R alpha

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
D7715A7

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
OKT4 hybridoma cells

Quantity:
0.2 mg

Research Discipline:
__

Target Species:
Mouse

Isotype:
IgG2b κ

Img

BD Biosciences

BDB554470

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Antigen:
CD132

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Interleukin Common γ chain, γc

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
TUGM2

Conjugate:
Biotin

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse IL-2Rγ Transfected Cell Line

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b κ