BDB556309
Nestin Mouse anti-Rat, Unlabeled, Clone: RAT 401, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB556309-Each-of-1 | In Stock | ₹ 32,855.04 |
BDB556309 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,855.04
GST (18%): ₹ 5,913.907
Total Price: ₹ 38,768.947
Antigen
Nestin
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Rat (E15) spinal cord extracts
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Rat
Isotype
IgG1
Applications
Western Blot
Clone
RAT 401
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Description
- Multipotential stem cells in the neural tube of the developing embryo give rise to the different neuronal cell types of the brain
- Nestin is an intermediate filament protein which is abundantly expressed in neuroepithelial stem cells early in embryogenesis, but is absent from nearly all mature central nervous system (CNS) cells
- After its down-regulation, GFAP and neurofilaments are expressed in differentiated astrocytes and neurons, respectively
- Initial studies showed that the mouse anti-rat nestin antibody (clone Rat 401) recognized transient radial glial cells and dividing neuroepithelial stem cells in the embryonic rat CNS
- Reportedly, Rat 401 has been used to analyze nestin expression in the developing rat nervous system and in immortalized CNS precursor cell lines (e.g such as in E11 rat CNS stem cells, but lost by postnatal day 6 (P6) in spinal cord and by P21 in the cerebellum)
- Although not expressed in normal adult CNS cells, nestin has been reportedly to be detectable in a variety of CNS tumors, suggesting that these tumors share gene expression patterns with primitive, undifferentiated CNS cells
- Rat 401 positive cells have been reported to be found throughout the developing neural tube, but not in the adult CNS
- More than 90% of dissociated E11 neural tube cells have been reported to be Rat 401 positive
- Rat 401 recognizes rat nestin and has been reported not to cross-react with human nestin
- Due to differential tissue expression, this antibody may recognize nestin as a doublet within a range of 198-260kDa
- Host Species: Mouse Clone: Rat 401 Isotype: IgG1 Species Reactivity: Rat Immunogen: Rat (E15) spinal cord extracts Electron Microscopy, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blotting
Compare Similar Items
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Antigen: Nestin
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Rat (E15) spinal cord extracts
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Rat
Isotype: IgG1
Applications: Western Blot
Clone: RAT 401
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Nestin
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Rat (E15) spinal cord extracts
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
RAT 401
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: Tau
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: __
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Rat
Isotype: IgG1
Applications: Western Blot
Clone: TAU-5
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Tau
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
__
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
TAU-5
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: MAP2
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Cow MAP2
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Bovine, Frog, Human, Quail, Rat
Isotype: IgG1
Applications: Western Blot
Clone: AP20
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
MAP2
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Cow MAP2
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Bovine, Frog, Human, Quail, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
AP20
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: β-Tubulin
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: __
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Bovine, Human, Mouse, Rat
Isotype: IgM κ
Applications: Western Blot
Clone: 5H1
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
β-Tubulin
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
__
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Bovine, Human, Mouse, Rat
Isotype:
IgM κ
Applications:
Western Blot
Clone:
5H1
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C