BDB556362

PARP Mouse, Unlabeled, Clone: C2-10, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB556362-Each-of-1 In Stock ₹ 34,052.88

BDB556362 - Each of 1

₹ 34,052.88

In Stock

Quantity

1

Base Price: ₹ 34,052.88

GST (18%): ₹ 6,129.518

Total Price: ₹ 40,182.398

Antigen

PARP

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Cow PARP (full-length; thymus derived)

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Isotype

IgG1

Applications

Western Blot

Clone

C2-10

Description

Poly (ADP-Ribose) Polymerase

Host Species

Mouse

Quantity

0.1 mL

Research Discipline

Cell Biology

Target Species

Bovine, Hamster, Human, Mouse

Form

Ascites

Description

  • PARP [Poly(ADP-Ribose) Polymerase] is a 113kDa nuclear chromatin associated enzyme that catalyzes the transfer of ADP-ribose units from NAD+ to a variety of nuclear proteins including topoisomerases, histones, and PARP itself
  • The catalytic activity of PARP is increased in nonapoptotic cells following DNA damage, and PARP is thought to play an important role in mediating the normal cellular reponse to DNA damage and is a target of the caspase protease activity associated with apoptosis
  • During apoptosis, PARP is cleaved from a 113kDa intact form into 89kDa and 24kDa fragments
  • This process separates the amino-terminal DNA-binding domain of the enzyme from the C-terminal catalytic domain resulting in the loss of normal PARP function
  • Although the role of PARP in apoptosis remains to be elucidated, PARP cleavage is considered to be a marker of apoptosis
  • This antibody has been reported to recognize an epitope located within the DNA-binding domain of the enzyme
  • Host Species: Mouse Clone: C2-10 Isotype: IgG1 Species Reactivity: Human Immunogen: Cow PARP (full-length; thymus derived) Immunofluorescence, Western Blotting

Compare Similar Items

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BD Biosciences

BDB556362

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Antigen:
PARP

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Cow PARP (full-length; thymus derived)

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Isotype:
IgG1

Applications:
Western Blot

Clone:
C2-10

Description:
Poly (ADP-Ribose) Polymerase

Host Species:
Mouse

Quantity:
0.1 mL

Research Discipline:
Cell Biology

Target Species:
Bovine, Hamster, Human, Mouse

Form:
Ascites

Img

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Monoclonal

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
ASC35

Description:
__

Host Species:
Mouse

Quantity:
0.1 mg

Research Discipline:
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Aqueous buffered solution containing ≤0.09% sodium azide.

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Primary or Secondary:
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Store undiluted at 4°C

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0.1 mg

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Antigen:
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Classification:
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Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Regulatory Status:
RUO

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C

Isotype:
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Applications:
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Clone:
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