BDB556597
DNA Topoisomerase I Mouse anti-Human, Unlabeled, Clone: C-21.2, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB556597-Each-of-1 | In Stock | ₹ 33,241.50 |
BDB556597 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,241.50
GST (18%): ₹ 5,983.47
Total Price: ₹ 39,224.97
Antigen
DNA Topoisomerase I
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Western Blot
Clone
C-21.2
Conjugate
Unconjugated
Host Species
Mouse
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgM
Description
- DNA damage may be caused by various environmental factors, including radiation, mutagenic chemicals and copy errors which occur during DNA replication
- The correction of DNA damage, so called “proofreading” functions of the cell, is achieved by numerous excision-repair enzymes
- Topoisomerases alter the helical structure of DNA by introducing the transient breaking and rejoining of DNA strands, allowing other excision-repair enzymes to correct DNA errors
- Topoisomerase I (Topo I) is a ubiquitous, soluble enzyme whose expression is fairly constant throughout the cell cycle
- The related enzyme, Topo II, is a primarily insoluble structural protein whose expression varies between cell types and during the cell cycle
- In addition to its role in DNA mismatch repair, Topo I displays kinase activity, phosphorylating serine-arginine rich (SR) splicing factors, and perhaps regulating gene expression by changing the splicing pattern of structural genes
- DNA Topo I migrates at a molecular weight of 100kDa in SDS-PAGE
- Clone C-21 recognizes human DNA Topoisomerase I
- The antibody is routinely tested by western blot analysis of A-431 cell lysates
- Host Species: Mouse Clone: C-21 Isotype: IgM Species Reactivity: Human Western Blotting
Compare Similar Items
Show Difference
Antigen: DNA Topoisomerase I
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: C-21.2
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgM
Antigen:
DNA Topoisomerase I
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
C-21.2
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgM
Antigen: NF-ATc2
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: 4G6-G5
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG2a κ
Antigen:
NF-ATc2
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
4G6-G5
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG2a κ
Antigen: NF-ATc1
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: 7A6
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1 κ
Antigen:
NF-ATc1
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
7A6
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1 κ
Antigen: MASH1
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: 24B7.2D11
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Mouse, Rat
Isotype: IgG1
Antigen:
MASH1
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
24B7.2D11
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Mouse, Rat
Isotype:
IgG1