BDB557451

CD244.2 Mouse anti-Mouse, Unlabeled, Clone: 2B4, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557451-Each-of-1 In Stock ₹ 14,031.84

BDB557451 - Each of 1

₹ 14,031.84

In Stock

Quantity

1

Base Price: ₹ 14,031.84

GST (18%): ₹ 2,525.731

Total Price: ₹ 16,557.571

Antigen

CD244.2

Classification

Monoclonal

Concentration

0.5mg/mL

Description

2B4 B6 Alloantigen

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

2B4

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

rIL-2-propagated NK1.1+ cells from C57BL/6 mice

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b κ

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Description

  • CD244 is a member of the CD2 subset of the immunoglobulin superfamily (CD2 IgSF)
  • It is expressed on all natural killer (NK) cells, IL-2-activated NK (LAK) cells, committed progenitors of NK cells, and a subset of T lymphocytes which mediate non-MHC-restricted cytoxicity, including dendritic epidermal T cells
  • The 2B4 antibody reacts with CD244.2, the 2B4 alloantigen which is expressed on C57BL/6 and C58/J mice, but not in most strains tested (A/J, AKR, BALB/c, CBA/J, CBA/N, C3H/He, C57BR, DBA/1, DBA/2, NZB, SJL/J, 129)
  • At least two isoforms of CD244.2 protein, products of alternative splicing of hnRNA, are expressed on IL-2-activated C57BL/6 NK cells
  • They differ only in their cytoplasmic domains; with 2B4L (150-aa cytoplasmic tail) having inhibitory activity and 2B4S (93-aa tail) being stimulatory
  • The extracellular domain of CD244 is a ligand for another CD2 IgSF member, CD48
  • 2B4 antibody activates lytic and secretory functions of IL-2-cultured NK cells and CD244.2+ T cells.

Compare Similar Items

Show Difference

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BD Biosciences

BDB557451

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Antigen:
CD244.2

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
2B4 B6 Alloantigen

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
2B4

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
rIL-2-propagated NK1.1+ cells from C57BL/6 mice

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b κ

Img

BD Biosciences

BDB557484

--


Antigen:
CD48

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
BLAST; BLAST-1; BCM1; HM48-1; MEM-102; Sgp-60; SLAMF2

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
HM48-1

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse T lymphoma MBL-2

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 λ3

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BD Biosciences

BDB557493

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Antigen:
CD103

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Itgae; Integrin alpha-E; αE; alpha-E1; ITAE; Integrin αIEL chain; aM290

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
M290

Conjugate:
Biotin

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse Intestinal Epithelial Cells

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

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BD Biosciences

BDB557498

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Antigen:
Integrin b7 chain

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Integrin βp

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
M293

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
αIELβ7 integrin from the C57BL/10 mouse T-cell hybridoma MTC-1

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ