BDB558139
GITR Rat anti-Mouse, FITC, Clone: DTA-1, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558139-Each-of-1 | In Stock | ₹ 32,683.92 |
BDB558139 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,683.92
GST (18%): ₹ 5,883.106
Total Price: ₹ 38,567.026
Antigen
GITR
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse CD25+ CD4+ T Cell Line
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2b
Applications
Flow Cytometry
Clone
DTA-1
Conjugate
FITC
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The DTA-1 antibody reacts with GITR [Glucocorticoid-induced Tumor necrosis factor (TNF) receptor family-Related], a 66-70kDa homodimer glycoprotein that is a member of the TNF receptor superfamily and is also known as TNFRSF18
- As its name implies, GITR expression was first detected in T lymphocytes that had been treated with dexamethasone, a glucocorticoid
- In normal naive mice, GITR is expressed at moderate levels on CD25-positive/CD4-positive/CD8a-negative thymocytes and on CD25-positive/CD4-positive/CD45RB-low splenocytes
- It is also expressed at low levels on splenic CD25-negative/CD4-positive/CD45RB-low T lymphocytes, B lymphocytes, macrophages, and dendritic cells
- Activation of T and B lymphocytes upregulates GITR expression
- GITR is a costimulatory receptor that plays an important role in Regulatory T (Treg)-cell functions, and a GITR Ligand has been detected on B lymphocytes, macrophages, and dendritic cells
- mAb DTA-1 abrogates suppression by Treg cells without affecting their proliferative response, while it is co-stimulatory for T lymphocytes that are not Treg cells
- Host Species: Rat Clone: DTA-1 Isotype: IgG2b, λ Cross Reactivity: Mouse Flow Cytometry
Compare Similar Items
Show Difference
Antigen: GITR
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse CD25+ CD4+ T Cell Line
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry
Clone: DTA-1
Conjugate: FITC
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
GITR
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse CD25+ CD4+ T Cell Line
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
DTA-1
Conjugate:
FITC
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Ly-6A/E
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: IL-2-dependent mouse T-cell line CTL-L
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: D7
Conjugate: PE-Cyanine7
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Ly-6A/E
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
IL-2-dependent mouse T-cell line CTL-L
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
D7
Conjugate:
PE-Cyanine7
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD117
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse Bone Marrow Mast Cells
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 2B8
Conjugate: PE-Cyanine7
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD117
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse Bone Marrow Mast Cells
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
2B8
Conjugate:
PE-Cyanine7
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD252
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human OX40 Ligand Transfected Cell Line
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: IK-1
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD252
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human OX40 Ligand Transfected Cell Line
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
IK-1
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.