BDB565151
CD357 (GITR) Rat anti-Mouse, Alexa Fluor 647, Clone: DTA-1, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565151-Each-of-1 | In Stock | ₹ 30,801.60 |
BDB565151 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,801.60
GST (18%): ₹ 5,544.288
Total Price: ₹ 36,345.888
Antigen
CD357
Classification
Monoclonal
Concentration
0.2mg/mL
Description
GITR; Gitr; glucocorticoid-induced TNFR-related protein; Tnfrsf18; AITR
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2b
Applications
Flow Cytometry
Clone
DTA-1
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse CD25+ CD4+ T Cell Line
Quantity
0.1 mg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The DTA-1 monoclonal antibody specifically binds to GITR [Glucocorticoid-induced Tumor necrosis factor (TNF) receptor family-Related], a 66-70-kDa homodimer glycoprotein that is a member of the TNF receptor superfamily and is also known as TNFRSF18 and CD357
- As its name implies, GITR expression was first detected in T lymphocytes that had been treated with dexamethasone, a glucocorticoid
- In normal naive mice, GITR is expressed at moderate levels on CD25-positive/CD4-positive/CD8a-negative thymocytes and on CD25-positive/CD4-positive/CD45RB-low splenocytes
- It is also expressed at low levels on splenic CD25-negative/CD4-positive/CD45RB-low T lymphocytes, B lymphocytes, macrophages, and dendritic cells
- Activation of T and B lymphocytes upregulates GITR expression
- GITR is a costimulatory receptor that plays an important role in Regulatory T (Treg)-cell functions, and a GITR Ligand has been detected on B lymphocytes, macrophages, and dendritic cells
- mAb DTA-1 abrogates suppression by Treg cells without affecting their proliferative response, while it is co-stimulatory for T lymphocytes that are not Treg cells.
Compare Similar Items
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Antigen: CD357
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: GITR; Gitr; glucocorticoid-induced TNFR-related protein; Tnfrsf18; AITR
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry
Clone: DTA-1
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse CD25+ CD4+ T Cell Line
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD357
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
GITR; Gitr; glucocorticoid-induced TNFR-related protein; Tnfrsf18; AITR
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
DTA-1
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse CD25+ CD4+ T Cell Line
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD226
Classification: Monoclonal
Concentration: __
Description: DNAM-1; DNAM1; PTA1; PTA-1; TLiSA1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: DX11
Conjugate: Brilliant Blue 515 (BB515)
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen: Human CTL Clone
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD226
Classification:
Monoclonal
Concentration:
__
Description:
DNAM-1; DNAM1; PTA1; PTA-1; TLiSA1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
DX11
Conjugate:
Brilliant Blue 515 (BB515)
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen:
Human CTL Clone
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD69
Classification: Monoclonal
Concentration: __
Description: Vol. Per test: 5μL
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: FN50 (also known as FN 50)
Conjugate: APC-R700
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen: __
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon APC-R700 under optimum conditions and unconjugated antibody and free BD Horizon APC-R700 were removed.
Antigen:
CD69
Classification:
Monoclonal
Concentration:
__
Description:
Vol. Per test: 5μL
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
FN50 (also known as FN 50)
Conjugate:
APC-R700
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon APC-R700 under optimum conditions and unconjugated antibody and free BD Horizon APC-R700 were removed.
Antigen: CD70
Classification: Monoclonal
Concentration: __
Description: CDw70; CD27 ligand; CD27-L; CD27L; CD27LG; Ki-24 antigen; TNFSF7
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG3 κ
Applications: Flow Cytometry
Clone: Ki-24
Conjugate: Brilliant Blue 515 (BB515)
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: __
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD70
Classification:
Monoclonal
Concentration:
__
Description:
CDw70; CD27 ligand; CD27-L; CD27L; CD27LG; Ki-24 antigen; TNFSF7
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG3 κ
Applications:
Flow Cytometry
Clone:
Ki-24
Conjugate:
Brilliant Blue 515 (BB515)
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
__
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.