BDB558071

NKG2D Mouse anti-Human, APC, Clone: 1D11, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558071-Each-of-1 In Stock ₹ 27,036.96

BDB558071 - Each of 1

₹ 27,036.96

In Stock

Quantity

1

Base Price: ₹ 27,036.96

GST (18%): ₹ 4,866.653

Total Price: ₹ 31,903.613

Antigen

NKG2D

Classification

Monoclonal

Conjugate

APC

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

1D11

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

NKL cells

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

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Description

  • The 1D11 monoclonal antibody specifically binds to NKG2D, a 42 kDa type II transmembrane glycoprotein that is also known as CD314 and KLRK1
  • NKG2D is a member of the C-type lectin family and is expressed on human NK cells
  • This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types
  • Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells
  • It is also expressed on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells
  • NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells
  • Importantly, NKG2D can complement the role of NCR in tumor cell lysis
  • Remarkably, the combined maskings of NCR and NKG2D can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
  • The 1D11 antibody can reportedly block or stimulate the function of NKG2D-positive cells.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB558071

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Antigen:
NKG2D

Classification:
Monoclonal

Conjugate:
APC

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1D11

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
NKL cells

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Img

BD

BDB558074

--


Antigen:
__

Classification:
Monoclonal

Conjugate:
APC

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
__

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
__

Formulation:
__

Immunogen:
__

Quantity:
1 Each

Research Discipline:
__

Target Species:
__

Isotype:
__

Img

Fischer Scientific

BDB558079

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Antigen:
CD11c

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
HL3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 λ2

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BD Biosciences

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Antigen:
Stat3 (pS727)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
49/P-STAT3

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human Stat3

Quantity:
50 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1