BDB558136
Stat4 (pY693) Mouse, Alexa Fluor 488, Clone: 38/P-STAT4, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558136-Each-of-1 | In Stock | ₹ 28,257.50 |
BDB558136 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,257.50
GST (18%): ₹ 5,086.35
Total Price: ₹ 33,343.85
Antigen
Stat4 (pY693)
Classification
Monoclonal
Conjugate
Alexa Fluor 488
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human Stat4 (pY693)
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human, Mouse
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
38/P-STAT4
Description
Signal transducer and activator of transcription 4; SLEB11
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The Stat proteins function both as cytoplasmic signal transducers and as activators of transcription
- Seven mammalian Stat proteins have been identified: Stat1-4, Stat5a, 5b, and Stat6
- Stat4 has been shown to play an important role in development of T helper cells, specifically the Th1 subset
- Stat4 is activated by IL-12 and by type 1 interferons
- Knockout mice supported the role that Stat4 plays in IL-12 signaling because lymphocytes from Stat 4-/- mice could not differentiate into Th1 cells or produce IFNγ in response to treatment with IL-12
- IFNγ plays an important role in host defense
- A key component in the activation of Stat4 is the phosphorylation on tyrosine and serine residues in response to IL-12 stimulation
- IL-12 stimulation leads to the phosphorylation of Stat4 on tyrosine 693 and serine 721
- Transcriptional activity of Stat4 has been shown to be significantly reduced when residues Y693 and S721 are mutated
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Mouse Clone: 38 Isotype: IgG2b κ Species Reactivity: Human, Mouse Immunogen: Phosphorylated Human Stat4 (pY693) Flow Cytometry, Intracellular Staining
Compare Similar Items
Show Difference
Antigen: Stat4 (pY693)
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Stat4 (pY693)
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 38/P-STAT4
Description: Signal transducer and activator of transcription 4; SLEB11
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Stat4 (pY693)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Stat4 (pY693)
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
38/P-STAT4
Description:
Signal transducer and activator of transcription 4; SLEB11
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Stat4 (pY693)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Stat4 (pY693)
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 38/P-STAT4
Description: Signal transducer and activator of transcription 4; SLEB11
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Stat4 (pY693)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Stat4 (pY693)
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
38/P-STAT4
Description:
Signal transducer and activator of transcription 4; SLEB11
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: GITR
Classification: Monoclonal
Conjugate: FITC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse CD25+ CD4+ T Cell Line
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry
Clone: DTA-1
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
GITR
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse CD25+ CD4+ T Cell Line
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
DTA-1
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Ly-6A/E
Classification: Monoclonal
Conjugate: PE-Cyanine7
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: IL-2-dependent mouse T-cell line CTL-L
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: D7
Description: Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Ly-6A/E
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
IL-2-dependent mouse T-cell line CTL-L
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
D7
Description:
Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.