BDB558249

Stat4 (pY693) Mouse, PE, Clone: 38/P-STAT4, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558249-Each-of-1 In Stock ₹ 27,165.30

BDB558249 - Each of 1

₹ 27,165.30

In Stock

Quantity

1

Base Price: ₹ 27,165.30

GST (18%): ₹ 4,889.754

Total Price: ₹ 32,055.054

Antigen

Stat4 (pY693)

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen

Phosphorylated Human Stat4 (pY693)

Quantity

50 Tests

Research Discipline

Cell Biology

Target Species

Human, Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

38/P-STAT4

Description

Signal transducer and activator of transcription 4; SLEB11

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The Stat proteins function both as cytoplasmic signal transducers and as activators of transcription
  • Seven mammalian Stat proteins have been identified: Stat1-4, Stat5a, 5b, and Stat6
  • Stat4 has been shown to play an important role in development of T helper cells, specifically the Th1 subset
  • Stat4 is activated by IL-12 and by type 1 interferons
  • Knockout mice supported the role that Stat4 plays in IL-12 signaling because lymphocytes from Stat 4-/- mice could neither differentiate into Th1 cells nor produce IFN-γ in response to treatment with IL-12
  • IFN-γ plays an important role in host defense
  • A key component in the activation of Stat4 is the phosphorylation on tyrosine and serine residues in response to IL-12 stimulation
  • IL-12 stimulation leads to the phosphorylation of Stat4 on tyrosine 693 and serine 721
  • Transcriptional activity of Stat4 has been shown to be significantly reduced when residues Y693 and S721 are mutated.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB558249

--


Antigen:
Stat4 (pY693)

Classification:
Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human Stat4 (pY693)

Quantity:
50 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
38/P-STAT4

Description:
Signal transducer and activator of transcription 4; SLEB11

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB558250

--


Antigen:
C3a

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
__

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
ELISA

Clone:
I87-1162

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB558251

--


Antigen:
C3a

Classification:
Monoclonal

Conjugate:
Biotin

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
__

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
ELISA

Clone:
I87-419

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB558257

--


Antigen:
CD3 ε

Classification:
Monoclonal

Conjugate:
APC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
APA1/1

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.