BDB558257

CD3ε Mouse anti-Human, APC, Clone: APA1/1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558257-Each-of-1 In Stock ₹ 33,197.28

BDB558257 - Each of 1

₹ 33,197.28

In Stock

Quantity

1

Base Price: ₹ 33,197.28

GST (18%): ₹ 5,975.51

Total Price: ₹ 39,172.79

Antigen

CD3 ε

Classification

Monoclonal

Conjugate

APC

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

APA1/1

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • Monoclonal antibody APA1/1 reacts with the intracellular domain of the epsilon chain of the CD3 molecule (CD3-ε)
  • This antibody does not react with the extracellular region of CD3-ε
  • The assembly of the T cell antigen receptor (TCR)-CD3 complex has been suggested to take place by pairwise interactions of the CD3-ε subunit with either CD3-γ or CD3-δ
  • These dimers then associate with the TCR heterodimer a/β or γε
  • Other anti-CD3 antibodies (OKT3, WT31, UCHT1, Leu4) did not react with COS cells singly transfected with CD3-ε
  • This reagent could be useful for the study of T cell development or the study of conformational changes of CD3-ε upon ligand binding to TCR-CD3 complex.

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