BDB558263

CD209 Mouse anti-Human, PerCP-Cy5.5, Clone: DCN46, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558263-Each-of-1 In Stock ₹ 37,475.28

BDB558263 - Each of 1

₹ 37,475.28

In Stock

Quantity

1

Base Price: ₹ 37,475.28

GST (18%): ₹ 6,745.55

Total Price: ₹ 44,220.83

Antigen

CD209

Classification

Monoclonal

Conjugate

PerCP-Cyanine5.5

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Monocyte Derived DC Cells

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

DCN46

Description

DC-SIGN

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The DCN46 antibody specifically binds to dendritic cell-specific ICAM-3 grabbing nonintegrin (DC-SIGN or CD209), a type-II membrane protein of approximately 44 kDa with a mannose-binding C-type lectin domain
  • It is highly expressed on dendritic cells in mucosal tissues
  • Its sequence is identical to the HIV-1 envelope gp120-binding C-type lectin, and reports suggest that DC-SIGN binds to HIV-1 gp120 and effectively transmits infectious HIV-1 to resting T lymphocytes expressing CD4 and chemokine receptors
  • The C-type lectin domain of DC-SIGN is also capable of binding other pathogenic viruses, bacteria, and parasites
  • Reports also suggest that DC-SIGN enables the highly efficient migration of dendritic cells from blood into the tissues
  • It can interact with ICAM-2, which has a similar sequence as ICAM-3, and is abundantly expressed on vascular and lymphoid endothelium
  • Thus, DC-SIGN mediates dendritic cells rolling and transendothelial migration, and its interaction with ICAM-2 is essential to specific migratory functions of dendritic cells.

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Show Difference

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Fischer Scientific

BDB558263

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Antigen:
CD209

Classification:
Monoclonal

Conjugate:
PerCP-Cyanine5.5

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Monocyte Derived DC Cells

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
DCN46

Description:
DC-SIGN

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB558264

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Immunogen:
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Research Discipline:
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Target Species:
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Isotype:
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Applications:
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Clone:
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Host Species:
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Applications:
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Clone:
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Purification Method:
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Antigen:
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Classification:
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Conjugate:
__

Formulation:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Target Species:
__

Isotype:
__

Applications:
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Clone:
__

Description:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Content And Storage:
2°C to 8°C