BDB558294

CD284/MD-2 Complex Rat anti-Mouse, PE, Clone: MTS510, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558294-Each-of-1 In Stock ₹ 22,416.72

BDB558294 - Each of 1

₹ 22,416.72

In Stock

Quantity

1

Base Price: ₹ 22,416.72

GST (18%): ₹ 4,035.01

Total Price: ₹ 26,451.73

Antigen

CD284/MD-2 Complex

Classification

Monoclonal

Concentration

0.2mg/mL

Description

TLR4/MD-2 Complex

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

MTS510

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse Pro-B cell line Ba/F3 e pressing transfected BALB/c mouse TLR4 and MD-2

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2a κ

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Description

  • Description The MTS510 antibody reacts with the molecular complex of Toll-Like Receptor 4 and MD-2 (TLR4-MD-2) which is expressed on LPS responsive macrophages
  • TLR4, a member of the Toll-Like Receptor Family, has been renamed as CD284 and identified to be the transmembrane signal-transducing portion of the receptor for LPS
  • TLR4 associates on the cell surface with CD14 and MD-2, a 0.7 kDa molecule which is anchored to the membrane via its physical association with TLR4
  • The association of MD-2 with TLR4 is required for recognition of LPS and the anti-mitotic compound Taxol, which mimics the action of LPS on mouse cells
  • MTS510 mAb detects TLR4-MD-2 on the surface of thioglycollate-elicited macrophages from all mouse strains tested (ie, BALB/c, C57BL/6, C3H/HeJ, C3H/HeN, and DBA/1), including the C3H/HeJ strain which expresses an LPS-resistant mutant TLR4
  • Expression of TLR4-MD-2 is down-regulated on peritoneal macrophages after exposure to LPS, correlating with the occurrence of LPS tolerance
  • TLR4-MD-2 is not detected on splenocytes or thymocytes.

Compare Similar Items

Show Difference

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BD Biosciences

BDB558294

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Antigen:
CD284/MD-2 Complex

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
TLR4/MD-2 Complex

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MTS510

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse Pro-B cell line Ba/F3 e pressing transfected BALB/c mouse TLR4 and MD-2

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

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BD Biosciences

BDB558295

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Antigen:
CD49b

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Integrin α2 chain

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
HMA2

Conjugate:
APC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse colon carcinoma cell line Colon26

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

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Antigen:
__

Classification:
__

Concentration:
__

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
__

Content And Storage:
Undiluted at 4°C

Applications:
Flow Cytometry

Clone:
27-35

Conjugate:
PerCP-Cyanine5.5

Formulation:
__

Immunogen:
__

Quantity:
100 Tests

Research Discipline:
__

Target Species:
__

Isotype:
IgG2b κ

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Antigen:
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Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Western Blot

Clone:
J1-223.371

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human Akt1 Peptide

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG1 κ