BDB558352
MIC A/B Mouse anti-Human, PE, Clone: 6D4, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558352-Each-of-1 | In Stock | ₹ 24,742.00 |
BDB558352 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,742.00
GST (18%): ₹ 4,453.56
Total Price: ₹ 29,195.56
Antigen
MIC A/B
Classification
Monoclonal
Conjugate
PE
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
6D4
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
MICA transfected cells
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The 6D4 monoclonal antibody specifically binds to the human MHC class I polypeptide-related sequence A (MICA, aka PERB11.1) and B (MICB
- aka PERB11.2) proteins
- These ∽70 kDa transmembrane glycoproteins are homologs of the major histocompatibility complex class I molecules although they lack association with β2 microglobulin
- The MHC class I-related MICA and MICB chains are expressed by some gut epithelial cells in vivo
- MICA and MICB expression by other epithelial cells and cell types, including fibroblasts and endothelial cells, is induced by stress, eg, stress caused by bacterial and viral infections, autoimmunity or cellular transformation
- Epithelial cell expression of MICA and MICB has also been detected in transplanted kidneys and pancreas that show histological signs of rejection and or cellular injury
- This suggests their potential role in transplant immunopathology
- MICA and MICB are ligands for NKG2D (CD314), an activating receptor expressed by natural killer (NK) cells, γδ T cells, CD8+ and some CD4+ αβ T cells
Compare Similar Items
Show Difference
Antigen: MIC A/B
Classification: Monoclonal
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 6D4
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: MICA transfected cells
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
MIC A/B
Classification:
Monoclonal
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
6D4
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
MICA transfected cells
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CREB (pS133) / ATF-1 (pS63)
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
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Applications: Western Blot
Clone: J151-21
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human CREB Peptide
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Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
CREB (pS133) / ATF-1 (pS63)
Classification:
Monoclonal
Conjugate:
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Host Species:
Mouse
Purification Method:
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Regulatory Status:
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Target Species:
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Isotype:
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Applications:
Western Blot
Clone:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
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Store undiluted at 4°C
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Purification Method: Affinity Purified
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Applications: Western Blot
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Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
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Content And Storage: Store undiluted at 4°C
Antigen:
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Conjugate:
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Host Species:
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Purification Method:
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Regulatory Status:
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Target Species:
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Applications:
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Clone:
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Formulation:
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Immunogen:
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Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
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Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
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Conjugate:
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Host Species:
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Purification Method:
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Target Species:
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Clone:
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Formulation:
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Immunogen:
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Quantity:
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Primary or Secondary:
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Content And Storage:
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