BDB558375
MEK1 (pS298) Mouse, Unlabeled, Clone: J114-64, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558375-Each-of-1 | In Stock | ₹ 50,374.00 |
BDB558375 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,374.00
GST (18%): ₹ 9,067.32
Total Price: ₹ 59,441.32
Antigen
MEK1 (pS298)
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Phosphorylated Human MEK1 Peptide
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human, Mouse
Isotype
IgG1 κ
Applications
Western Blot
Clone
J114-64
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Description
- MEK (Map/Erk Kinase) 1 and 2 are serine/threonine kinases, also known as MAP kinase kinases (MAP2K1 and 2, MAPKK1 and 2, or MKK1 and 2)
- They activate the MAP (Mitogen-Activated Protein) kinases, also known as ERKs (Extracellular signal Regulated Kinases), which are critical kinases in multiple signal transduction pathways that regulate cell growth and differentiation
- Activation of MEK 1 and 2 is dependent upon phosphorylation of serines 218 and/or 222 by activated MAP kinase kinase kinases (MAP3Ks), such as the Raf isoforms
- Hormones, growth and differentiating factors, or tumor promoters induce Raf activation via activation of Ras proteins
- Alternatively, cellular adhesion can lead to phosphorylation of MEK1 at serine 298 (S298), mediated by p21-activated kinase (PAK)
- The S298-phosphorylated MEK1 has an enhanced capacity to interact with Raf, resulting in MEK1 activation
- The J114-64 monoclonal antibody recognizes the phosphorylated S298 of MEK1
- Western Blotting
Compare Similar Items
Show Difference
Antigen: MEK1 (pS298)
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human MEK1 Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1 κ
Applications: Western Blot
Clone: J114-64
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
MEK1 (pS298)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human MEK1 Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
J114-64
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: NF-κB p65 (pS536)
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human or Mouse NF-κB p65 Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Applications: Western Blot
Clone: J144-460
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
NF-κB p65 (pS536)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human or Mouse NF-κB p65 Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
J144-460
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: IRS-1 (pY896)
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human IRS-1 Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a κ
Applications: Western Blot
Clone: K9-211
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
IRS-1 (pY896)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human IRS-1 Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
K9-211
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: EGF Receptor (pY845)
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human EGF Receptor Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Applications: Western Blot
Clone: 12A3
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
EGF Receptor (pY845)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human EGF Receptor Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
12A3
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C