BDB558690

CD23 Mouse anti-Human, APC, Clone: M-L233, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB558690-Each-of-1 In Stock ₹ 31,956.66

BDB558690 - Each of 1

₹ 31,956.66

In Stock

Quantity

1

Base Price: ₹ 31,956.66

GST (18%): ₹ 5,752.199

Total Price: ₹ 37,708.859

Antigen

CD23

Classification

Monoclonal

Conjugate

APC

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

M-L233

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The M-L233 antibody specifically binds to human CD23, the low affinity receptor for human IgE (FcεRII)
  • CD23 is a type II membrane glycoprotein that can be expressed by B cells, monocytes, macrophages, eosinophils, platelets and dendritic cells
  • CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils
  • Soluble CD23 (sCD23) can be released by CD23-positive cells as a result of proteolytic cleavage of membrane CD23
  • Larger fragments of sCD23 (e.g., 25-37 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not
  • Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.

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Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.