BDB560091

PDPK1 (pS241) Mouse, Alexa Fluor 647, Clone: J66-653.44.17, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB560091-Each-of-1 In Stock ₹ 27,036.96

BDB560091 - Each of 1

₹ 27,036.96

In Stock

Quantity

1

Base Price: ₹ 27,036.96

GST (18%): ₹ 4,866.653

Total Price: ₹ 31,903.613

Antigen

PDPK1 (pS241)

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Phosphorylated Human PDPK1 Peptide

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

J66-653.44.17

Description

PDK1 (pS241), PKB Kinase (pS241)

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse, Rat

Isotype

IgG1 κ

Description

  • The serine/threonine kinase 3- Phosphoinositide- Dependent Protein Kinase-1 (PDPK1, also known as PDK1) contributes to the activation of many important kinases in the insulin and IGF-1 signaling pathways
  • It acts downstream of phosphatidylinositol 3-kinase (PI3-kinase) to phosphorylate residues in the activation loops of many cellular kinases, including protein kinase B (PKB/Akt), PKC isoforms, p70 S6 kinase, and PDPK1 itself
  • The autophosphorylation of PDPK1 at serine 241 (S241) has recently been suggested to play a role in the regulation of PDPK1
  • It has been proposed that PDPK1 activity plays a key role in the regulation of various cellular events such as cell proliferation, differentiation, and apoptosis
  • The J666-653.44.17 monoclonal antibody recognizes the phosphorylated S241 in the activation loop of human PDPK1
  • The orthologous phosphorylation site in mouse and rat PDPK1 is S244.

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Antigen:
PDPK1 (pS241)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human PDPK1 Peptide

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
J66-653.44.17

Description:
PDK1 (pS241), PKB Kinase (pS241)

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Isotype:
IgG1 κ

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Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

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Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Clone:
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Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

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Description:
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Host Species:
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Purification Method:
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Isotype:
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