BDB560212

Granzyme B Mouse anti-Human, Alexa Fluor 647, Clone: GB11, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB560212-Each-of-1 In Stock ₹ 31,956.66

BDB560212 - Each of 1

₹ 31,956.66

In Stock

Quantity

1

Base Price: ₹ 31,956.66

GST (18%): ₹ 5,752.199

Total Price: ₹ 37,708.859

Antigen

Granzyme B

Classification

Monoclonal

Concentration

0.2mg/mL

Description

GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

GB11

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human Granzyme B

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

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Description

  • Description The GB11 antibody specifically reacts with human granzyme B, a serine protease of approximately 32 kDa
  • Granzyme B is stored in the granules of cytotoxic T lymphocytes and NK cells along with the pore-forming protein perforin
  • In the classic model of target cell lysis, perforins create holes in the target cell membrane allowing entrance of granzymes
  • Granzyme B has been shown to act on specific substrates including caspase-3, -7, -9, and -10 which in turn give rise to enzymes that mediate apoptosis
  • Granzyme B may also be involved in the hydrolysis of extracellular matrix components
  • Detectable levels of granzyme B have been detected in sera from healthy volunteers
  • The immunogen used to generate the GB11 hybridoma was human granzyme B isolated from an NK cell line.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB560212

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Antigen:
Granzyme B

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
GB11

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human Granzyme B

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Img

Fischer Scientific

BDB560220

--


Antigen:
IL-17A

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
TC11-18H10

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant Mouse IL-17A Protein

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Img

Fischer Scientific

BDB560221

--


Antigen:
IL-17A

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
TC11-18H10

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant Mouse IL-17 Protein

Quantity:
25 μg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Img

Fischer Scientific

BDB560224

--


Antigen:
IL-17A

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
TC11-18H10

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant Mouse IL-17A Protein

Quantity:
25 μg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ