BDB560241
p38 MAPK (pT180/pY182) Mouse, PE-Cy7, Clone: 36/P38 (PT180/PY182), BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560241-Each-of-1 | In Stock | ₹ 27,036.96 |
BDB560241 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,036.96
GST (18%): ₹ 4,866.653
Total Price: ₹ 31,903.613
Antigen
p38 MAPK (pT180/pY182)
Classification
Monoclonal
Conjugate
PE-Cyanine7
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human p38 MAPK (pT180/pY182) Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human, Mouse, Rat
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
36/P38 (PT180/PY182)
Description
MAPK14; p38 MAP kinase; p38 MAPK; RK; CSBP2
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- Activation of the immune and inflammatory responses often involves the recognition of bacterial endotoxin (lipopolysaccharide or LPS)
- Binding of LPS by monocytes results in the production and release of proinflammatory cytokines, such as IL-1 and TNF
- LPS-induced signaling cascades involve members of the Ser/Thr protein kinase family known as the Mitogen Activated Protein Kinases (MAPKs)
- MAPK signal transduction pathways mediate the effects of various extracellular stimuli on biological processes such as proliferation, differentiation, and death
- The p38 MAPKs include p38α (MAPK14), β (MAPK11), γ (MAPK12), and δ (MAPK13)
- These Ser/Thr kinases are activated by dual phosphorylation on threonine (T) and tyrosine (Y) within the motif Thr-Gly-Tyr located in kinase subdomain VIII
- Activation of p38 MAPK is mediated specifically by the MAP Kinase Kinases, MKK3, MKK4, and MKK6
- This leads to the activation of multiple transcription factors (NF-κB, ATF-2, Elk-1, and CHOP) that induce expression of many different genes, including proinflammatory cytokine genes
- Thus, p38 MAPKs are central kinases in multiple signal transduction pathways
- The 36/p38 (pT180/pY182) monoclonal antibody recognizes the conserved dual phosphorylated site pT180/pY182 of p38α, β, γ, and δ
- Host Species: Mouse Clone: 36 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Phosphorylated Human p38 MAPK (pT180/pY182) Peptide Intracellular Staining
Compare Similar Items
Show Difference
Antigen: p38 MAPK (pT180/pY182)
Classification: Monoclonal
Conjugate: PE-Cyanine7
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human p38 MAPK (pT180/pY182) Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 36/P38 (PT180/PY182)
Description: MAPK14; p38 MAP kinase; p38 MAPK; RK; CSBP2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
p38 MAPK (pT180/pY182)
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human p38 MAPK (pT180/pY182) Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
36/P38 (PT180/PY182)
Description:
MAPK14; p38 MAP kinase; p38 MAPK; RK; CSBP2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: PKCα
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Human PKCα aa. 270-427 Recombinant Protein
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 3/PKC
Description: Protein Kinase C α, PKC-α, PKC-A, PKCA, PRKCA
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
PKCα
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Human PKCα aa. 270-427 Recombinant Protein
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
3/PKC
Description:
Protein Kinase C α, PKC-α, PKC-A, PKCA, PRKCA
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD19
Classification: Monoclonal
Conjugate: APC-H7
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Mouse CD19 Transfected Cell Line
Quantity: 25 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 1D3
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD19
Classification:
Monoclonal
Conjugate:
APC-H7
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Mouse CD19 Transfected Cell Line
Quantity:
25 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
1D3
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD16
Classification: Monoclonal
Conjugate: APC-H7
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Human polymorphonuclear leukocytes
Quantity: 25 μg
Research Discipline: Immunology
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 3G8
Description: FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD16
Classification:
Monoclonal
Conjugate:
APC-H7
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Human polymorphonuclear leukocytes
Quantity:
25 μg
Research Discipline:
Immunology
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
3G8
Description:
FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.