BDB560422

Nestin Mouse, Alexa Fluor 555, Clone: 25/NESTIN, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB560422-Each-of-1 In Stock ₹ 44,362.86

BDB560422 - Each of 1

₹ 44,362.86

In Stock

Quantity

1

Base Price: ₹ 44,362.86

GST (18%): ₹ 7,985.315

Total Price: ₹ 52,348.175

Antigen

Nestin

Classification

Monoclonal

Conjugate

Alexa Fluor 555

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

In vitro Assay

Clone

25/NESTIN

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen

Rat Nestin aa. 402-604 Recombinant Protein

Quantity

100 Tests

Research Discipline

Cell Biology

Target Species

Human, Rat

Isotype

IgG1 κ

Description

  • The cytoskeleton consists primarily of core structural proteins that include microfilaments, microtubules, and intermediate filaments (IFs)
  • IFs contain more than 50 distinct proteins that are organized into six different subtypes: Type I/II keratins expressed in epithelia, type III vimentin/desmin, type IV neurofilament proteins, type V nuclear lamins, and type VI nestin expressed primarily in embryonic cells
  • Nestin has a conserved core region (amino acids 7 to 314), which contains an α helical domain that is involved in coiled-coil assembly of IFs
  • The C-terminal region of nestin is similar to type IV IFs, since it contains highly charged amino acids, many glutamate residues, and an 11 amino acid repeat motif
  • Nestin is expressed in the cerebrum during embryonic development, in the cerebellum during early postnatal development, and in dermatomal cells and myoblasts during myogenesis
  • In vitro, nestin forms homodimers and homotetramers, but not IFs, and can co-assemble with type III vimentin and type IV internexin proteins
  • Thus, nestin is a core IF protein that is essential for proper cytoskeletal formation during neurogenesis and myogenesis
  • Host Species: Mouse Clone: 25 Isotype: IgG1 κ Species Reactivity: Rat Immunogen: Rat Nestin aa
  • 402-604 Recombinant Protein Bioimaging

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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In vitro Assay

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Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

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100 Tests

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IgG1 κ

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Flow Cytometry

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