BDB560618
NK-1.1 Mouse anti-Mouse, APC-Cy7, Clone: PK136, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560618-Each-of-1 | In Stock | ₹ 14,605.09 |
BDB560618 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,605.09
GST (18%): ₹ 2,628.916
Total Price: ₹ 17,234.006
Antigen
NK-1.1
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Klrb1b, CD161b, Nkrp1b; Klrb1c, CD161c, NK1.1, Nkrp1c
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
PK136
Conjugate
APC-Cyanine7
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
Mouse NK-1+ Spleen and Bone Marrow Cells
Quantity
50 μg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Description
- In the mouse, at least three members of the Klrb (Killer cell lectin-like receptor, subfamily b; formerly NKR-P1) gene family have been identified (Klrb1a/NKR-P1A, Klrb1b/NKR-P1B, and Klrb1c/NKR-P1C); but in the human gene family, a single homologue has been designated KLRB1, NKR-P1A, or CD161
- The KLRB1/NKR-P1 family of proteins are type-II-transmembrane C-type lectin receptors
- KLRB1C/NKR-P1C activates NK-cell cytotoxicity, while KLRB1B/NKR-P1B functions as an inhibitory receptor
- KLRB1B/NKR-P1B protein has intracellular Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), while KLRB1C/NKR-P1C lacks ITIM and activates via association with Fc Receptor γ chain
- Strikingly, KLRB1B/NKR-P1B and KLRB1C/NKR-P1C share 96% amino acid sequence identity in their extracellular C-type lectin domains
- The PK136 antibody reacts with the NK-1.1 surface antigen encoded by the Klrb1c/NKR-P1C gene expressed on natural killer (NK) cells in selected strains of mice (eg, C57BL, FVB/N, NZB, but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, NOD, SJL, 129) and the antigen encoded by the Klrb1b/NKR-P1B gene expressed only on Swiss NIH and SJL mice, but not on C57BL/6
- Expression of KLRB1C/NKR-P1C protein is correlated with the ability to lyse tumor cells in vitro and to mediate rejection of bone marrow allografts
- The NK-1.1 marker is useful in defining NK cells; however, the antigen is also expressed on a rare, specialized population of T lymphocytes (NK-T cells) and some cultured monocytes
- Plate-bound PK136 mAb, in combination with low concentrations of IL-2, induces proliferation of a subset of NK cells
- Flow Cytometry
Compare Similar Items
Show Difference
Antigen: NK-1.1
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Klrb1b, CD161b, Nkrp1b; Klrb1c, CD161c, NK1.1, Nkrp1c
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: PK136
Conjugate: APC-Cyanine7
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Mouse NK-1+ Spleen and Bone Marrow Cells
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
NK-1.1
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Klrb1b, CD161b, Nkrp1b; Klrb1c, CD161c, NK1.1, Nkrp1c
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
PK136
Conjugate:
APC-Cyanine7
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Mouse NK-1+ Spleen and Bone Marrow Cells
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: CD196
Classification: Monoclonal
Concentration: __
Description: BN-1; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; CD196
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 11A9
Conjugate: PE-Cyanine7
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human CD196/CCR6 Peptide
Quantity: 50 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD196
Classification:
Monoclonal
Concentration:
__
Description:
BN-1; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; CD196
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
11A9
Conjugate:
PE-Cyanine7
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human CD196/CCR6 Peptide
Quantity:
50 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Vα2 TCR
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: B20.1
Conjugate: PE-Cyanine7
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Soluble αβ TCR from mouse cytotoxic T-cell clone KB5-C20
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a λ
Antigen:
Vα2 TCR
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
B20.1
Conjugate:
PE-Cyanine7
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Soluble αβ TCR from mouse cytotoxic T-cell clone KB5-C20
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a λ
Antigen: Caspase-3
Classification: Monoclonal
Concentration: __
Description: CPP32; Yama; Apopain
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: C92-605
Conjugate: Violet Fluor 450 (V450)
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Human Active Caspase-3 Fragment
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG
Antigen:
Caspase-3
Classification:
Monoclonal
Concentration:
__
Description:
CPP32; Yama; Apopain
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
C92-605
Conjugate:
Violet Fluor 450 (V450)
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Human Active Caspase-3 Fragment
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG