BDB560620

CD196 (CCR6) Mouse anti-Human, PE-Cy7, Clone: 11A9, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB560620-Each-of-1 In Stock ₹ 15,571.92

BDB560620 - Each of 1

₹ 15,571.92

In Stock

Quantity

1

Base Price: ₹ 15,571.92

GST (18%): ₹ 2,802.946

Total Price: ₹ 18,374.866

Antigen

CD196

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human CD196/CCR6 Peptide

Quantity

50 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

11A9

Description

BN-1; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; CD196

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The 11A9 monoclonal antibody specifically binds to CCR6
  • CCR6 is a seven-transmembrane, G-protein-coupled, glycoprotein receptor that is a member of the beta chemokine receptor family
  • CCR6 was clustered as CD196 in the 7th HLDA Workshop
  • The human CCR6 gene has been mapped to chromosome 6q27
  • CCR6 is a receptor for the CC chemokine CCL20/MIP-3alpha/LARC/Exodus and also binds with lower affinity to and mediates responses to beta-defensin2/hBD-2
  • CCR6 is predominantly expressed by B lymphocytes, certain subsets of effector and memory T cells and by immature dendritic cells but not by monocytes, NK cells, or granulocytyes
  • Skin-homing CLA (Cutaneous Lymphocyte Antigen)-positive memory T cells, Th1 cells, regulatory T cells and IL-17A-producing Th17 cells predominantly express high levels of CCR6
  • CCR6 mediates the trafficking of T, B, and dendritic cells to epithelial sites near the skin and mucosal surfaces during inflammatory and immunological responses
  • An N-terminal peptide of human CCR6 was used as an immunogen to generate the 11A9 hybridoma
  • The 11A9 antibody does not cross-react with human CCR1, CCR2, CCR3, CCR4, CCR5, CCR7, CCR8, CCR9, CXCR1, CXCR2, CXCR3, CXCR4 and CXCR5 receptors
  • This antibody is NOT a neutralizing antibody.

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BDB560620

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Antigen:
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Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human CD196/CCR6 Peptide

Quantity:
50 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
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Description:
BN-1; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; CD196

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Aqueous buffered solution containing ≤0.09% sodium azide.

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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