BDB560887

FoxP3 Mouse anti-Human, Alexa Fluor 488, Clone: 259D/C7, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB560887-Each-of-1 In Stock ₹ 14,947.33

BDB560887 - Each of 1

₹ 14,947.33

In Stock

Quantity

1

Base Price: ₹ 14,947.33

GST (18%): ₹ 2,690.519

Total Price: ₹ 17,637.849

Antigen

FoxP3

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

FoxP3 recombinant protein

Quantity

25 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

259D/C7

Description

Scurfin, IPEX, JM2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype

IgG1

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Description

  • The 259D/C7 antibody reacts with the human FoxP3 transcription factor, a member of the forkhead or winged helix family of transcription factors
  • The expression of FoxP3, also known as Scurfin, IPEX and JM2, has been found to be associated with CD4+ regulatory T cells and represents a specific marker for these cells
  • Flow-cytometric analysis has shown that FoxP3 is expressed by the majority of CD4+CD25+high T cells in peripheral blood while less than half of CD4+CD25int cell population are FoxP3 positive
  • Approximately 5-10% of peripheral CD4+ cells are CD4+CD25+ T regulatory cells
  • T regulatory cells are thought to play a critical role in the control of T cell mediated autoimmunity by suppressing the proliferation and cytokine production of other T cells
  • To support this hypothesis, it has been found that FOXP3 is mutated in scurfy (sf) mice
  • The 259D/C7 antibody reacts with all currently identified isoforms of human FoxP3 and is cross-reactive with Cynomolgus, Rhesus and Baboon.

Compare Similar Items

Show Difference

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Fischer Scientific

BDB560887

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Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
FoxP3 recombinant protein

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
259D/C7

Description:
Scurfin, IPEX, JM2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1

Img

Fischer Scientific

BDB560889

--


Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
FoxP3 recombinant protein

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
259D/C7

Description:
Scurfin, IPEX, JM2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1

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BD Biosciences

BDB560892

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Antigen:
__

Classification:
__

Conjugate:
Alexa Fluor 647

Formulation:
__

Immunogen:
__

Quantity:
0.1 mg

Primary or Secondary:
__

Content And Storage:
4°C

Applications:
Flow Cytometry

Clone:
R4-22

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
__

Target Species:
__

Isotype:
IgM κ

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BDB560895

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Antigen:
CD11c

Classification:
Monoclonal

Conjugate:
APC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Spleen Cells from Human with Hairy Cell Leukemia

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
B-ly6

Description:
ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ