BDB560047

FoxP3 Mouse anti-Human, Alexa Fluor 488, Clone: 259D/C7, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB560047-Each-of-1 In Stock ₹ 32,855.04

BDB560047 - Each of 1

₹ 32,855.04

In Stock

Quantity

1

Base Price: ₹ 32,855.04

GST (18%): ₹ 5,913.907

Total Price: ₹ 38,768.947

Antigen

FoxP3

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

FoxP3 recombinant protein

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

259D/C7

Description

Scurfin, IPEX, JM2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype

IgG1

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Description

  • The 259D/C7 antibody reacts with the human FoxP3 transcription factor, a member of the forkhead or winged helix family of transcription factors
  • The expression of FoxP3, also known as Scurfin, IPEX and JM2, has been found to be associated with CD4+ regulatory T cells and represents a specific marker for these cells
  • Flow-cytometric analysis has shown that FoxP3 is expressed by the majority of CD4+CD25+high T cells in peripheral blood while less than half of CD4+CD25int cell population are FoxP3 positive
  • Approximately 5-10% of peripheral CD4+ cells are CD4+CD25+ T regulatory cells
  • T regulatory cells are thought to play a critical role in the control of T cell mediated autoimmunity by suppressing the proliferation and cytokine production of other T cells
  • To support this hypothesis, it has been found that FOXP3 is mutated in scurfy (sf) mice
  • The 259D/C7 antibody reacts with all currently identified isoforms of human FoxP3 and is cross-reactive with Cynomolgus, Rhesus and Baboon.

Compare Similar Items

Show Difference

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Fischer Scientific

BDB560047

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Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
FoxP3 recombinant protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
259D/C7

Description:
Scurfin, IPEX, JM2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1

Img

BD Biosciences

BDB560053

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Antigen:
TIE2 (pY1102)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human TIE2 Peptide

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
K93-754

Description:
TEK, VMCM, CD202b

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG2a κ

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BD Biosciences

BDB560058

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Antigen:
SLP-76

Classification:
Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human SLP-76 SH2 domain Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
H3

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG2a κ

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BDB560061

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Antigen:
E-Cadherin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Human E-Cadherin C-terminal Recombinant Protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
36/E-Cadherin

Description:
CD324; CDH1; CADH1; Cadherin-1; ECAD; CDHE; Arc-1; LCAM; UVO; Uvomorulin

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Isotype:
IgG2a κ