BDB561690

CD11b Rat anti-Mouse, APC, Clone: M1/70, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561690-Each-of-1 In Stock ₹ 8,590.22

BDB561690 - Each of 1

₹ 8,590.22

In Stock

Quantity

1

Base Price: ₹ 8,590.22

GST (18%): ₹ 1,546.24

Total Price: ₹ 10,136.46

Antigen

CD11b

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

M1/70

Conjugate

APC

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen

Mouse Splenic Cells

Quantity

25 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The M1/70 monoclonal antibody specifically binds to CD11b, also known as Integrin alpha M (Itgam or α;M)
  • CD11b is a 170-kDa type 1 transmembrane glycoprotein and belongs to the Integrin alpha chain family
  • CD11b serves as the alpha chain of the heterodimeric Mac-1 integrin (CD11b/CD18, α;Mβ;2), also known as complement receptor 3 (CR3)
  • Mac-1 mediates adhesion to ICAM-1 (CD54), ICAM-2 (CD102), fibrinogen and binding to C3bi
  • Mac-1 is expressed at varying levels on granulocytes, macrophages, myeloid-derived dendritic cells, natural killer cells, microglia, and B-1 B lymphocytes
  • Mac-1 expression is rapidly up-regulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface
  • The M1/70 antibody reportedly blocks cell adherence and C3bi binding but does not block cell-mediated lysis
  • Cross-reaction of the M1/70 antibody with CD11b expressed on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB561690

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Antigen:
CD11b

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
M1/70

Conjugate:
APC

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Mouse Splenic Cells

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Fischer Scientific

BDB561691

--


Antigen:
CD11b/c

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Rat

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
OX-42

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Resident peritoneal cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB561693

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Antigen:
CD122

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Il2rb; Il-2Rbeta; IL-2Rβ; IL-15Rbeta; IL-2/15 Receptor-beta; IL-2/15Rbeta

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
TM-β 1

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse IL-2Rβ Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB561694

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Antigen:
CD123

Classification:
Monoclonal

Concentration:
__

Description:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
7G3

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human IL-3Ra-transfected cells

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.