BDB561998
Granzyme B Mouse anti-Human, FITC, Clone: GB11, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561998-Each-of-1 | In Stock | ₹ 14,062.00 |
BDB561998 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,062.00
GST (18%): ₹ 2,531.16
Total Price: ₹ 16,593.16
Antigen
Granzyme B
Classification
Monoclonal
Conjugate
FITC
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
GB11
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Granzyme B
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- Description The GB11 antibody specifically reacts with human granzyme B, a serine protease of approximately 32 kDa
- Granzyme B is stored in the granules of cytotoxic T lymphocytes and NK cells along with the pore-forming protein perforin
- In the classic model of target cell lysis, perforins create holes in the target cell membrane allowing entrance of granzymes
- Granzyme B has been shown to act on specific substrates including caspase-3, -7, -9, and -10 which in turn give rise to enzymes that mediate apoptosis
- Granzyme B may also be involved in the hydrolysis of extracellular matrix components
- Detectable levels of granzyme B have been detected in sera from healthy volunteers
- The immunogen used to generate the GB11 hybridoma was human granzyme B isolated from an NK cell line.
Compare Similar Items
Show Difference
Antigen: Granzyme B
Classification: Monoclonal
Conjugate: FITC
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: GB11
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human Granzyme B
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Granzyme B
Classification:
Monoclonal
Conjugate:
FITC
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
GB11
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human Granzyme B
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Granzyme B
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: GB11
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human Granzyme B
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Granzyme B
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
GB11
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human Granzyme B
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: H-2D[d]
Classification: Monoclonal
Conjugate: FITC
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 34-2-12
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: (C57BL/6 x DBA/2)F1 mouse splenocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
H-2D[d]
Classification:
Monoclonal
Conjugate:
FITC
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
34-2-12
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
(C57BL/6 x DBA/2)F1 mouse splenocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: H-2Kb
Classification: Monoclonal
Conjugate: FITC
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: AF6-88.5
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Mouse C57BL splenocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
H-2Kb
Classification:
Monoclonal
Conjugate:
FITC
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
AF6-88.5
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Mouse C57BL splenocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.