BDB562064

NKG2D Mouse anti-Human, APC, Clone: 1D11, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562064-Each-of-1 In Stock ₹ 14,031.84

BDB562064 - Each of 1

₹ 14,031.84

In Stock

Quantity

1

Base Price: ₹ 14,031.84

GST (18%): ₹ 2,525.731

Total Price: ₹ 16,557.571

Antigen

NKG2D

Classification

Monoclonal

Conjugate

APC

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

1D11

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

NKL cells

Quantity

25 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 1D11 monoclonal antibody specifically binds to NKG2D, a 42 kDa type II transmembrane glycoprotein that is also known as CD314 and KLRK1
  • NKG2D is a member of the C-type lectin family and is expressed on human NK cells
  • This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types
  • Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells
  • It is also expressed on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells
  • NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells
  • Importantly, NKG2D can complement the role of NCR in tumor cell lysis
  • Remarkably, the combined maskings of NCR and NKG2D can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
  • The 1D11 antibody can reportedly block or stimulate the function of NKG2D-positive cells.

Compare Similar Items

Show Difference

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Fischer Scientific

BDB562064

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Antigen:
NKG2D

Classification:
Monoclonal

Conjugate:
APC

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
1D11

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
NKL cells

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB562065

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Antigen:
p38 MAPK

Classification:
Monoclonal

Conjugate:
PE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
36/p38 (pT180/pY182)

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human p38 MAPK (pT180/pY182) Peptide

Quantity:
250 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
Siglec-F

Classification:
Monoclonal

Conjugate:
PE

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
E50-2440

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse Siglec-F and human IgG Fc recombinant fusion protein

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
Stat1

Classification:
Monoclonal

Conjugate:
PE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
4a

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human Stat1 Peptide

Quantity:
250 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.