BDB562059
Ly-6A/E Rat anti-Mouse, PE, Clone: D7, BD
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562059-Each-of-1 | In Stock | ₹ 8,556.00 |
BDB562059 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 8,556.00
GST (18%): ₹ 1,540.08
Total Price: ₹ 10,096.08
Antigen
Ly-6A/E
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
D7
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
IL-2-dependent mouse T-cell line CTL-L
Quantity
25 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The D7 antibody reacts with Ly-6A.2 and Ly-6E.1, which are allelic members of the Ly-6 multigene family
- Sca-1 (Ly6A/E), a phosphatidylinositol-anchored protein of about 18 kDa, is expressed on the multipotent hematopoietic stem cells (HSC) in the bone marrow of mice with both Ly-6 haplotypes
- In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129), Ly-6A/E is also expressed on distinct subpopulations of bone marrow and peripheral B lymphocytes and thymic and peripheral T lymphocytes
- Strains with the Ly-6.1 haplotype (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Ly-6A/E+ resting peripheral lymphocytes, whereas activation of lymphocytes from mice of both Ly-6 haplotypes leads to strong expression of the Sca-1 antigen
- Studies with the D7 antibody have demonstrated that Ly-6A/E may be involved in the regulation of B and T lymphocyte responses, and it appears to be required for T-cell receptor-mediated T-cell activation
- Purified E13-161.7 mAb (anti-Ly-6A/E, Cat
- No
- 553333) can block binding of FITC-conjugated D7 antibody (Cat
- No
- 557405) to mouse splenocytes, but purified mAb D7 is unable to block binding of FITC-conjugated E13-161.7 antibody (Cat
- No
- 553335)
- Anti-Ly-6A/E (Sca-1) mAb may be used in combination with the Mouse Lineage Panel (Cat
- No
- 559971) to identify HSC
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Compare Similar Items
Show Difference
Antigen: Ly-6A/E
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: D7
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: IL-2-dependent mouse T-cell line CTL-L
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Ly-6A/E
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
D7
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
IL-2-dependent mouse T-cell line CTL-L
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Ly-6G and Ly-6C
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: Ly6c, Lymphocyte antigen 6C2; Lymphocyte antigen 6G, Ly6g, Gr-1
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: RB6-8C5
Conjugate: FITC
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Not Reported
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Ly-6G and Ly-6C
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
Ly6c, Lymphocyte antigen 6C2; Lymphocyte antigen 6G, Ly6g, Gr-1
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
RB6-8C5
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Not Reported
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: NK-1.1
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Klrb1b, CD161b, Nkrp1b; Klrb1c, CD161c, NK1.1, Nkrp1c
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: PK136
Conjugate: PE-Cyanine7
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse NK-1+ Spleen and Bone Marrow Cells
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
NK-1.1
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Klrb1b, CD161b, Nkrp1b; Klrb1c, CD161c, NK1.1, Nkrp1c
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
PK136
Conjugate:
PE-Cyanine7
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse NK-1+ Spleen and Bone Marrow Cells
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: NKG2D
Classification: Monoclonal
Concentration: __
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 1D11
Conjugate: APC
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: NKL cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
NKG2D
Classification:
Monoclonal
Concentration:
__
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
1D11
Conjugate:
APC
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
NKL cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.