BDB562260

LAP Mouse anti-Human, PE, Clone: TW4-2F8, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562260-Each-of-1 In Stock ₹ 33,539.52

BDB562260 - Each of 1

₹ 33,539.52

In Stock

Quantity

1

Base Price: ₹ 33,539.52

GST (18%): ₹ 6,037.114

Total Price: ₹ 39,576.634

Antigen

LAP

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human TGF-β1

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

TW4-2F8

Description

Latency-associated peptide; TGFB1; TGFbeta; Transforming growth factor beta

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The TW4-2F8 monoclonal antibody specifically binds to Latency-Associated Peptide (LAP), a component of the dimeric Transforming Growth Factor-beta 1 (TGF-β1) propeptide encoded by TGF-β1
  • Prior to secretion, the dimeric LAP-TGF-β1 propeptide is cleaved resulting in a biologically inactive form of dimeric TGF-β1 that is noncovalently associated with dimeric LAP (latent TGF-β1)
  • This complex may be expressed on the surface of TGF-β1-producing cells or be further processed by proteolytic removal of LAP to release the biologically active mature form of the soluble TGF-β1 homodimer
  • Platelets contain TGF-β1 and most nucleated cells, including tumor cells and cells that comprise the innate and adaptive immune system can produce TGF-ββ1
  • TGF-β1 is a potent multifunctional cytokine that regulates numerous processes including development, hematopoiesis, tissue remodeling, wound repair, and immunity as well as cancer and autoimmune diseases
  • The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed
  • Host Species: Mouse Clone: TW4-2F8 IsoType: Isotype: Mouse (BALB/c) IgG1κ Immunogen: Human TGF-β1 Cross Reactivity: Human Flow Cytometry

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Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

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Immunology

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Human

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Flow Cytometry

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Affinity Purified

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RUO

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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