BDB562150
GARP Mouse anti-Human, PE, Clone: 7B11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562150-Each-of-1 | In Stock | ₹ 38,673.12 |
BDB562150 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,673.12
GST (18%): ₹ 6,961.162
Total Price: ₹ 45,634.282
Antigen
GARP
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Recombinant Human LRRC32
Quantity
100 Tests
Research Discipline
Immunology
Target Species
Human
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
7B11
Description
LRRC32; Garpin; Glycoprotein A repetitions predominant
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 7B11 (also known as CMSSC-7B11) monoclonal antibody specifically binds to human GARP (Glycoprotein A repetitions predominant)
- The LRRC32 (Leucine rich repeat containing 32) gene encodes the 662 amino acid-residue, 80 kDa transmembrane GARP glycoprotein that has an extracellular region composed primarily of 20 leucine-rich repeats
- GARP is specifically expressed on Treg cellss activated through the T cell receptor (TCR)
- Ectopic expression of GARP in human na+»ve T cells inhibited their proliferation and cytokine secretion upon TCR activation
- Remarkably, GARP over-expression in na+»ve T cells induced expression of FoxP3 and endowed them with a partial suppressive function
- The extracellular, but not the cytoplasmic region, of GARP was necessary for these functions
- GARP serves as a receptor for latent TGF-beta which may play a role in the suppressive action of Treg cells
- GARP is also expressed on platelets and other tissues, however the function on these cells is not known
- The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed
- Host Species: Mouse Clone: 7B11 IsoType: Isotype: Mouse (BALB/c) IgG2bκ Immunogen: GARP Cross Reactivity: Human Flow Cytometry
Compare Similar Items
Show Difference
Antigen: GARP
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Recombinant Human LRRC32
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 7B11
Description: LRRC32; Garpin; Glycoprotein A repetitions predominant
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
GARP
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Recombinant Human LRRC32
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
7B11
Description:
LRRC32; Garpin; Glycoprotein A repetitions predominant
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD183
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse CXCR3 peptide (amino acids 1-37)
Quantity: 0.1 mg
Research Discipline: __
Target Species: Mouse
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: CXCR3-173
Description: CXCR3; Cxcr3; CXC-R3; CXCR-3; GPR9; IP-10 Receptor
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD183
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse CXCR3 peptide (amino acids 1-37)
Quantity:
0.1 mg
Research Discipline:
__
Target Species:
Mouse
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
CXCR3-173
Description:
CXCR3; Cxcr3; CXC-R3; CXCR-3; GPR9; IP-10 Receptor
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: IL-10
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Recombinant Rat IL-10
Quantity: 50 μg
Research Discipline: __
Target Species: Rat
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: A5-4
Description: Il10; Interleukin-10; CSIF; Cytokine synthesis inhibitory factor
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
IL-10
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Recombinant Rat IL-10
Quantity:
50 μg
Research Discipline:
__
Target Species:
Rat
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
A5-4
Description:
Il10; Interleukin-10; CSIF; Cytokine synthesis inhibitory factor
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD110
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: __
Quantity: 0.1 mg
Research Discipline: __
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 1.6.1
Description: C-MPL; MPL; MPLV; TPOR; Thrombopoietin receptor
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD110
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
0.1 mg
Research Discipline:
__
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
1.6.1
Description:
C-MPL; MPL; MPLV; TPOR; Thrombopoietin receptor
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.