BDB563956
GARP Mouse anti-Human, Brilliant Violet 421, Clone: 7B11, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563956-Each-of-1 | In Stock | ₹ 36,619.68 |
BDB563956 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,619.68
GST (18%): ₹ 6,591.542
Total Price: ₹ 43,211.222
Antigen
GARP
Classification
Monoclonal
Conjugate
Brilliant Violet 421
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Recombinant Human LRRC32
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
7B11
Description
LRRC32; Garpin; Glycoprotein A repetitions predominant
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2b κ
Related Products
Description
- The 7B11 (also known as CMSSC-7B11) monoclonal antibody specifically binds to human GARP (Glycoprotein A repetitions predominant)
- The LRRC32 (Leucine rich repeat containing 32) gene encodes the 662 amino acid-residue, 80 kDa transmembrane GARP glycoprotein that has an extracellular region composed primarily of 20 leucine-rich repeats
- GARP is specifically expressed on Treg cells activated through the T cell receptor (TCR)
- Ectopic expression of GARP in human naοve T cells inhibited their proliferation and cytokine secretion upon TCR activation
- Remarkably, GARP over-expression in naοve T cells induced expression of FoxP3 and endowed them with a partial suppressive function
- The extracellular, but not the cytoplasmic region, of GARP was necessary for these functions
- GARP serves as a receptor for latent TGF-beta which may play a role in the suppressive action of Treg cells
- GARP is also expressed on platelets and other tissues, however the function on these cells is not known.
Compare Similar Items
Show Difference
Antigen: GARP
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Recombinant Human LRRC32
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 7B11
Description: LRRC32; Garpin; Glycoprotein A repetitions predominant
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
GARP
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Recombinant Human LRRC32
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
7B11
Description:
LRRC32; Garpin; Glycoprotein A repetitions predominant
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: GARP
Classification: Monoclonal
Conjugate: Brilliant Violet 711
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Recombinant Human LRRC32
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 7B11
Description: LRRC32; Garpin; Glycoprotein A repetitions predominant
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
GARP
Classification:
Monoclonal
Conjugate:
Brilliant Violet 711
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Recombinant Human LRRC32
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
7B11
Description:
LRRC32; Garpin; Glycoprotein A repetitions predominant
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CLA
Classification: Monoclonal
Conjugate: __
Formulation: __
Immunogen: Lymphocyte-depleted Stromal Preparation of Tonsil
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: __
Applications: __
Clone: HECA-452
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: __
Antigen:
CLA
Classification:
Monoclonal
Conjugate:
__
Formulation:
__
Immunogen:
Lymphocyte-depleted Stromal Preparation of Tonsil
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
__
Applications:
__
Clone:
HECA-452
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
__
Antigen: CLA
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: __
Immunogen: Lymphocyte-depleted Stromal Preparation of Tonsil
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: __
Applications: __
Clone: HECA-452
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: __
Antigen:
CLA
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
__
Immunogen:
Lymphocyte-depleted Stromal Preparation of Tonsil
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
__
Applications:
__
Clone:
HECA-452
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
__