BDB562152

CD183 Hamster anti-Mouse, PE, Clone: CXCR3-173, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562152-Each-of-1 In Stock ₹ 28,405.92

BDB562152 - Each of 1

₹ 28,405.92

In Stock

Quantity

1

Base Price: ₹ 28,405.92

GST (18%): ₹ 5,113.066

Total Price: ₹ 33,518.986

Antigen

CD183

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CXCR3; Cxcr3; CXC-R3; CXCR-3; GPR9; IP-10 Receptor

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

CXCR3-173

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse CXCR3 peptide (amino acids 1-37)

Quantity

0.1 mg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The CXCR3-173 monoclonal antibody specifically binds to mouse CD183, also known as CXCR3
  • CD183 is a seven transmembrane spanning, G protein-coupled chemokine receptor for CXC chemokines including CXCL9 (Mig), CXCL10 (IP-10) and CXCL11 (I-TAC)
  • These chemokines are induced by inflammatory cytokines including IFN-γ, IFN-α/β, and TNF
  • CXCR3 is primarily expressed on activated/memory CD4+ and CD8+ T lymphocytes, Foxp+ regulatory T cells, natural killer T (NKT) cells and mature NK cells
  • Binding of chemokines to CXCR3 induces integrin activation, cytoskeletal changes, and chemotactic migration of activated lymphocytes
  • CD183 has been reported to play important roles in T cell recruitment and immune responses in a number of inflammatory and autoimmune diseases
  • The CXCR3-173 antibody reportedly inhibited in vitro chemotactic responses to CXCL10 or CXCL11 significantly but not to CXCL9
  • When administered systemically to mouse hosts, the CXCR3-173 antibody reportedly prolonged cardiac and pancreatic islet cell allograft survival
  • In the presence of CXCR3 ligands, especially, CXCL10 and CXCL11, staining with the antibody can be significantly blocked.

Compare Similar Items

Show Difference

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BD Biosciences

BDB562152

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Antigen:
CD183

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CXCR3; Cxcr3; CXC-R3; CXCR-3; GPR9; IP-10 Receptor

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
CXCR3-173

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse CXCR3 peptide (amino acids 1-37)

Quantity:
0.1 mg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB562156

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Antigen:
IL-10

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Il10; Interleukin-10; CSIF; Cytokine synthesis inhibitory factor

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Rat

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
A5-4

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant Rat IL-10

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB562159

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Antigen:
CD110

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
C-MPL; MPL; MPLV; TPOR; Thrombopoietin receptor

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
1.6.1

Conjugate:
PE

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
0.1 mg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB562161

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Antigen:
PDX-1

Classification:
Monoclonal

Concentration:
__

Description:
PDX1, GSF, IPF-1, IPF1, IUF-1, IDX-1, STF-1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
658A5

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human PDX-1 Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.