BDB562937

CD183 Hamster anti-Mouse, Brilliant Violet 421, Clone: CXCR3-173, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562937-Each-of-1 In Stock ₹ 25,154.64

BDB562937 - Each of 1

₹ 25,154.64

In Stock

Quantity

1

Base Price: ₹ 25,154.64

GST (18%): ₹ 4,527.835

Total Price: ₹ 29,682.475

Antigen

CD183

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CXCR3; Cxcr3; Cd183; Cmkar3; C-X-C chemokine receptor type 3

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1

Applications

Flow Cytometry

Clone

CXCR3-173

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Mouse CXCR3 peptide (amino acids 1–37)

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The CXCR3-173 monoclonal antibody specifically binds to mouse CD183, also known as CXCR3
  • CD183 is a seven transmembrane spanning, G protein-coupled chemokine receptor for CXC chemokines including CXCL9 (Mig), CXCL10 (IP-10) and CXCL11 (I-TAC)
  • These chemokines are induced by inflammatory cytokines including IFN- γ, IFN- α / β , and TNF
  • CXCR3 is primarily expressed on activated/memory CD4+ and CD8+ T lymphocytes, Foxp+ regulatory T cells, natural killer T (NKT) cells and mature NK cells
  • Binding of chemokines to CXCR3 induces integrin activation, cytoskeletal changes, and chemotactic migration of activated lymphocytes
  • CD183 has been reported to play important roles in T cell recruitment and immune responses in a number of inflammatory and autoimmune diseases
  • The CXCR3-173 antibody reportedly inhibited in vitro chemotactic responses to CXCL10 or CXCL11 significantly but not to CXCL9
  • When administered systemically to mouse hosts, the CXCR3-173 antibody reportedly prolonged cardiac and pancreatic islet cell allograft survival
  • In the presence of CXCR3 ligands, especially, CXCL10 and CXCL11, staining with the antibody can be significantly blocked.

Compare Similar Items

Show Difference

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BD Biosciences

BDB562937

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Antigen:
CD183

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CXCR3; Cxcr3; Cd183; Cmkar3; C-X-C chemokine receptor type 3

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
CXCR3-173

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Mouse CXCR3 peptide (amino acids 1–37)

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB562939

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Antigen:
CD31

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
PECAM-1

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
MEC 13.3

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
129/Sv mouse-derived endothelioma cell line tEnd.1

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD66B

Classification:
Monoclonal

Concentration:
__

Description:
CEACAM8; CGM6; NCA-95

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
G10F5

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Granulocytes

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD52

Classification:
Monoclonal

Concentration:
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Description:
Cambridge pathology 1 Ag; CAMPATH-1; Epididymal secretory protein E5; HE5

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG3 κ

Applications:
Flow Cytometry

Clone:
4C8

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Human T Lymphocytes

Quantity:
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Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.