BDB562519

Ly-49H Mouse anti-Mouse, PE-CF594, Clone: 3D10, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562519-Each-of-1 In Stock ₹ 21,133.32

BDB562519 - Each of 1

₹ 21,133.32

In Stock

Quantity

1

Base Price: ₹ 21,133.32

GST (18%): ₹ 3,803.998

Total Price: ₹ 24,937.318

Antigen

Ly-49H

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Ly49h; Lymphocyte antigen 49H; Klra8; Cmv1; Cmv-1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

3D10

Conjugate

PE-CF594

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Mouse Ly-49A/H Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 3D10 monoclonal antibody specifically binds to mouse Lymphocyte antigen 49H (Ly-49H; also known as Klra8 or Killer cell lectin-like receptor 8)
  • The 3D10 antibody does not crossreact with related molecules such as Ly-49A, C, D or G2
  • Ly-49H is a type II transmembrane protein and a member of the Ly-49 C-type lectin multigene family of receptors expressed by NK cells
  • Cell surface Ly-49H is expressed by a subset of NK cells but not by NKT cells
  • Ly-49H is expressed by C57BL/6 and NWNA but not by BALB/c or DBA/2 mouse NK cells
  • Cell surface Ly-49H presents as a ∽110kDa disfulfide-linked homodimer and associates with signaling subunits such as DAP10 and DAP12 for optimal transduction of intracellular activation signals
  • Crosslinking of Ly-49H with the 3D10 antibody reportedly induces NK cell cytotoxicity and cytokine production
  • Ly-49H recognizes the mouse cytomegalovirus m157 glycoprotein that is expressed by infected cells and is required for protection against cytomegalovirus infection
  • This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
  • PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
  • Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488nm), green (532nm) and yellow-green (561nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20nm filter)
  • Host Species: Mouse Clone: 3D10 Isotype: IgG1, κ Species Reactivity: Mouse Immunogen: Mouse Ly-49A/H Transfected Cell Line Flow Cytometry

Compare Similar Items

Show Difference

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BD Biosciences

BDB562519

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Antigen:
Ly-49H

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ly49h; Lymphocyte antigen 49H; Klra8; Cmv1; Cmv-1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
3D10

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Mouse Ly-49A/H Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
TNP

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
__

Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
__

Isotype:
IgG1 λ

Applications:
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Clone:
G235-2356

Conjugate:
PE-CF594

Formulation:
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Immunogen:
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Quantity:
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Primary or Secondary:
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Antigen:
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Classification:
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Concentration:
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Description:
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Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
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Target Species:
Mouse

Isotype:
IgG2 κ

Applications:
Flow Cytometry

Clone:
J43

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
DO-11.10 Clonotypic TCR

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
DO-11.10 clonotypic TCR

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
KJ1-26

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Quantity:
50 μg

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.