BDB562870
CD324 Mouse anti-Human, PE, Clone: 67A4, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562870-Each-of-1 | In Stock | ₹ 26,823.06 |
BDB562870 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,823.06
GST (18%): ₹ 4,828.151
Total Price: ₹ 31,651.211
Antigen
CD324
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Breast Tumor Cell Line
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
67A4
Description
E-cadherin
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 67A4 monoclonal antibody recognizes the extracellular domain of human E-Cadherin (CD324)
- E-Cadherin is a 120-kDa transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells
- There it interacts with the cytoskeleton through the associated cytoplasmic catenin proteins
- In addition to being a calcium-dependent adhesion molecule, E-Cadherin is also a critical regulator of epithelial junction formation
- Its association with catenins is necessary for cell-to-cell adhesion
- These E-Cadherin/catenin complexes associate with cortical actin bundles at both the zonula adherens and the lateral adhesion plaques
- Tyrosine phosphorylation can disrupt these complexes, leading to changes in cell adhesion properties
- E-Cadherin expression is often down-regulated in highly invasive, poorly differentiated carcinomas
- Increased expression of E-Cadherin in these cells reduces their invasiveness
- Thus, loss of expression or function of E-Cadherin appears to be an important step in tumorigenic progression
- Pluripotent stem cells express E-Cadherin
- Upon differentiation, an epithelial to mesenchymal transition results in the loss of E-cadherin expression and a gain in the expression of N-cadherin.
Compare Similar Items
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Antigen: CD324
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human Breast Tumor Cell Line
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 67A4
Description: E-cadherin
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD324
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human Breast Tumor Cell Line
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
67A4
Description:
E-cadherin
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD64
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 10.1
Description: FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD64
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
10.1
Description:
FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD20
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human 6.16c1.3 B cell line
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 2H7
Description: MS4A1; B1; Bp35; LEU-16; S7
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD20
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human 6.16c1.3 B cell line
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
2H7
Description:
MS4A1; B1; Bp35; LEU-16; S7
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD16
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human polymorphonuclear leukocytes
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 3G8
Description: FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG1 κ
Antigen:
CD16
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human polymorphonuclear leukocytes
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
3G8
Description:
FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG1 κ