BDB562903

Lgr5 (N-Terminal) Rat anti-Human, Alexa Fluor 647, Clone: 8F2, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB562903-Each-of-1 In Stock ₹ 24,299.04

BDB562903 - Each of 1

₹ 24,299.04

In Stock

Quantity

1

Base Price: ₹ 24,299.04

GST (18%): ₹ 4,373.827

Total Price: ₹ 28,672.867

Antigen

Lgr5 (N-Terminal)

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen

Human LGR5 DNA

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

8F2

Description

GPR49, GPR67, HG38

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

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Description

  • Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) is a seven transmembrane-domain receptor that is a target gene for Wnt and marks stem cells in the small intestine, colon, stomach, and hair follicle
  • Lgr5 was initially identified as a potential stem cell marker due to restricted expression of Lgr5 in the intestinal crypt and labeling of rapidly cycling cells of the colon and intestine
  • Using both lineage tracing and organoid culture experiments, Lgr5 positive cells are capable of generating all types of the small intestine epithelium hence indicating that Lgr5 marks stem cells of the small intestine and colon
  • R-spondin growth factors, which are secreted agonists of the Wnt pathway, bind Lgr5
  • The binding of R-spondins to Lgr5 leads to recruitment of the Frizzled/LRP Wnt receptor complex, which binds to Wnt ligands and leads to downstream Wnt signaling
  • Lgr5 is up-regulated in colon and ovarian cancers and has been implicated in promotion of tumor growth and metastasis
  • The 8F2 monoclonal antibody recognizes an epitope in the N-terminal region of Human Lgr5
  • Host Species: Rat Clone: 8F2 Isotype: IgG2b, κ Species Reactivity: Hu Immunogen: Human LGR5 DNA Flow Cytometry

Compare Similar Items

Show Difference

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BD Biosciences

BDB562903

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Antigen:
Lgr5 (N-Terminal)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Human LGR5 DNA

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
8F2

Description:
GPR49, GPR67, HG38

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

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BD Biosciences

BDB562906

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Antigen:
CD194

Classification:
Monoclonal

Conjugate:
Brilliant Violet 605

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human CCR4 Transfected Cell Line

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1G1

Description:
CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5

Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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Classification:
Monoclonal

Conjugate:
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Formulation:
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Immunogen:
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Quantity:
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Primary or Secondary:
Primary

Content And Storage:
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Applications:
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Clone:
hTNFR-M1

Description:
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Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b

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Antigen:
CD62L

Classification:
Monoclonal

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
C3H/eb mouse B lymphoma 38C-13

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MEL-14

Description:
Sell; L-selectin; LECAM-1; LAM-1; Lnhr; Ly-22; Ly-m22; Lyam-1

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ