BDB563063
CD49B Rat anti-Mouse, Brilliant Violet 421, Clone: DX5, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563063-Each-of-1 | In Stock | ₹ 23,400.66 |
BDB563063 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,400.66
GST (18%): ₹ 4,212.119
Total Price: ₹ 27,612.779
Antigen
CD49B
Classification
Monoclonal
Concentration
0.2mg/mL
Description
itga2; Integrin alpha-2; DX5; Pan NK cell marker; VLAA2; VLA-2 alpha chain
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgM κ
Applications
Flow Cytometry
Clone
DX5
Conjugate
Brilliant Violet 421
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Mouse (C57BL/6) NK1.1+ cells propagated with rIL-2
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The rat anti-mouse CD49b monoclonal antibody (clone DX5) specifically binds t o the integrin α2 chain (CD49b)
- C D49b is a 150 kDa transmembrane glycoprotein that non-covalently ass ociates with CD29 (integrin β1) to form the integrin α2β1 complex known as VLA-2
- The rat anti-mouse CD49b antibody (clone DX5) has been reported to identify the majority of NK cells and a small T-cell subpopulation in most mouse strains (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, DBA/1, DBA/2, SJL, SWR, 129/J, but not NOD)
- The DX5 antibody also recognizes platelets that express high levels of CD49b
- Multiparameter flow cytometric analysis has demonstrated that most lymphocytes which express NK-1.1 (NKR-P1B and NKR-P1C), as detectable by mouse anti-mouse NK-1.1 antibody (clone PK136), also express the DX5 antigen
- Small DX5+ NK-1.1- and DX5- NK-1.1+ cell subsets are found, especially among the CD3-positive cell population
- Some CD49b+ NK cells have been reported to gradually lose reactivity with the rat anti-mouse CD49b antibody (clone DX5) when cultured in the presence of recombinant human IL-2
- The resulting DX5-negative cells have weakened cytotoxic activity when compared to the remaining DX5+ cells
- This indicates that the DX5 antibody distinguishes functional subsets of NK cells
- No activation or blocking activity of the rat anti-mouse antibody (clone DX5) has been observed
- Staining of splenic NK cells with this antibody reportedly can be blocked by hamster anti-mouse CD49b antibody (clone HMα2).
Compare Similar Items
Show Difference
Antigen: CD49B
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: itga2; Integrin alpha-2; DX5; Pan NK cell marker; VLAA2; VLA-2 alpha chain
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgM κ
Applications: Flow Cytometry
Clone: DX5
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Mouse (C57BL/6) NK1.1+ cells propagated with rIL-2
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD49B
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
itga2; Integrin alpha-2; DX5; Pan NK cell marker; VLAA2; VLA-2 alpha chain
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgM κ
Applications:
Flow Cytometry
Clone:
DX5
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Mouse (C57BL/6) NK1.1+ cells propagated with rIL-2
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD194
Classification: Monoclonal
Concentration: __
Description: CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 1G1
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human CCR4 Transfected Cell Line
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD194
Classification:
Monoclonal
Concentration:
__
Description:
CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
1G1
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human CCR4 Transfected Cell Line
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD8a
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Cd8a; CD8 alpha chain; Ly-2; Lyt2; Lyt-2; Ly-35; Ly-B
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 53-6.7
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Mouse thymus / spleen Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD8a
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Cd8a; CD8 alpha chain; Ly-2; Lyt2; Lyt-2; Ly-35; Ly-B
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
53-6.7
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Mouse thymus / spleen Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD90
Classification: Monoclonal
Concentration: __
Description: THY1; Thy-1 antigen; Thy-1 membrane glycoprotein
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 5.00E+10
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human HEL Cell Line
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD90
Classification:
Monoclonal
Concentration:
__
Description:
THY1; Thy-1 antigen; Thy-1 membrane glycoprotein
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
5.00E+10
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human HEL Cell Line
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.